Titre :
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Association between low plasma vitamin E concentration and progression of early cortical lens opacities. (1996)
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Auteurs :
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P. ROUHIAINEN ;
H. ROUHIAINEN ;
J.T. SALONEN ;
The Research Institute of Public Health. University of Kuopio. Kuopio. FIN
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Type de document :
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Article
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Dans :
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American journal of epidemiology (vol. 144, n° 5, 1996)
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Pagination :
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496-500
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Langues:
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Anglais
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Mots-clés :
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Cataracte
;
Epidémiologie
;
Homme
;
Antioxydant
;
Vitamine
;
Finlande
;
Europe
;
Oeil [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST xBR0x1Tf. Diffusion soumise à autorisation]. The authors evaluated the association between plasma vitamin E content and progression of eye lens opacities. A total of 410 hypercholesterolemic eastern Finnish men participated in the study from January 1990 to September 1993 in Kuopio, Finland. Lens opacities were classified three times at 18-month intervals using the Lens Opacities Classification System II. A low plasma vitamin E level (lowest quartile) was associated with a 3.7-fold excess risk (95% confidence interval 1.2-11.8) of the progression of early cortical lens opacities compared with the highest quartile (p=0.028). In addition, the number of cigarettes smoked daily was a significant predictor of the progression of cortical lens opacity (relative risk=1.06 per cigarette, 95% confidence interval 1.003-1.12). The progression of nuclear lens opacities was not associated with either the plasma vitamin E content or smoking. The data suggest that low plasma vitamin E content may be associated with increased risk of the progression of early cortical lens opacity.
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