Résumé :
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[BDSP. Notice produite par INIST tX6R0xbC. Diffusion soumise à autorisation]. This population-based case-control study examined the association between selected nutrients, foods, and diet behaviors and bladder cancer. Bladder cancer cases (n=262) were identified from the Surveillance, Epidemiology, and End Results Program cancer registry for western Washington, and controls (n=405) were identified through random digit dialing. Cases were diagnosed between January 1987 and June 1990, and eligible subjects were Caucasian, aged 45-65 years, and residents of King, Pierce, or Snohomish counties. Subjects completed a self-administered, 71-item food frequency questionnaire and a structured telephone interview. Analyses were conducted by logistic regression analysis and included adjustment for age, sex, smoking (current, former, never), and county. Odds ratios and their 95% confidence intervals for highest versus lowest level of intake were examined. An inverse association was found between the risk of bladder cancer and dietary retinol (odds ratio (OR) across quartiles : 1.00,1.09,0.97, and 0.52 ; 95% CI 0.29-0.97 ; trend p value=0.03) and dietary vitamin C (OR across quartiles : 1.00,0.96,0.67, and 0.50 ; 95% CI 0.28-0.88 ; trend p value=0.009), adjusted for calories. The use of multivitamin supplements daily over the 10-year period ending 2 years before diagnosis versus no use was associated with a decreased risk of bladder cancer (OR=0.39 ; 95% Cl 0.24-0.63) as was use of supplemental vitamin C (OR for>502 mg/day over the 10 years vs. none=0. (...)
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