Titre :
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The relationship between plasma cholesterol concentration and minor psychiatric disturbance in the Department of the Environment Study. (1996)
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Auteurs :
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R.H. HARWOOD ;
C.J. BULPITT ;
A.E. FLETCHER ;
H.L.J. MARKOWE ;
M.G. MARMOT ;
M.J. SHIPLEY ;
Department of Epidemiology and Population Science. London School of Hygiene and Tropical Medicine. London. GBR
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Type de document :
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Article
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Dans :
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Journal of clinical epidemiology (vol. 49, n° 7, 1996)
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Pagination :
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795-801
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Langues:
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Anglais
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Mots-clés :
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Santé mentale
;
Epidémiologie
;
Homme
;
Taux
;
Cholestérol
;
Lipide
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Résumé :
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[BDSP. Notice produite par INIST 70R0xYnI. Diffusion soumise à autorisation]. We examined the hypothesis that low plasma cholesterol concentration was associated with minor psychiatric disturbance in a cross-sectional study of 410 male and 138 female civil servants. Psychiatric disturbance was measured using the 30-item General Health Questionnaire (GHQ). Mean GHQ score did not vary significantly with quartile of total cholesterol concentration. After adjustment for confounding variables a significant trend of increasing mean GHQ with increasing cholesterol concentration emerged. In a logistic regression analysis subjects in the highest quartile of cholesterol concentration had an adjusted odds ratio for being a "psychiatric case" of 2.0 (95% confidence interval, 1.1-2.5) compared with those in the lowest quartile. This relationship reversed when using a higher cutoff point to define more severe cases, although the trend was not statistically significant.
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