Titre :
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Soluble tumor necrosis factor alpha receptors (sTNF-Rs) in HIV-1-infected intravenous drug users : Change in circulating sTNF-R type II level and survival for AIDS patients. (2000)
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Auteurs :
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F. AJELLO ;
F. BONURA ;
M. BRUNO ;
R. LA LICATA ;
M. LODATO ;
N. ROMANO ;
R. VALENTI ;
F. Vitale ;
Dipartimento di Igiene e Microbiologia "G D'Alessandro". Università degli Studi. Palermo. ITA
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Type de document :
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Article
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Dans :
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European journal of epidemiology (vol. 16, n° 3, 2000)
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Pagination :
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209-216
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Langues:
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Anglais
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Mots-clés :
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Sida
;
Virose
;
Infection
;
VIH
;
Rétrovirus
;
Virus
;
Toxicomanie
;
Concentration
;
Plasma sanguin
;
Survie
;
Epidémiologie
;
Pronostic
;
Toxicomane
;
Homme
;
Italie
;
Europe
;
Immunopathologie
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Résumé :
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[BDSP. Notice produite par INIST PR0xid60. Diffusion soumise à autorisation]. This study in intravenous drug users (IVDUs) investigated differences in serum soluble tumor necrosis factor types I and II (sTNFR-I and II) concentrations in HIV-1-infected IVDUs and controls. This study also investigated whether changes of sTNFRs concentration affect the risk of death among patients with AIDS. A cross-sectional study of 54 subjects with AIDS, 47 HIV-seropositive IVDUs, 47 HIV-seronegative IVDUs, and 21 healthy subjects showed that sTNFRs concentration increases from healthy controls to AIDS patients through HIV-seronegative and HIV-seropositive subjects (p
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