Titre :
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Lifetime environmental exposure to tobacco smoke and primary lung cancer of non-smoking Taiwanese women. (2000)
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Auteurs :
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C.H. LEE ;
W. GOGGINS ;
J.J. HUANG ;
M.S. HUANG ;
E.L. KAO ;
Y.C. KO ;
H.Z. WANG ;
Department of Internal Medical. Kaohsiung Medical University. Kaohsiung. TWN ;
Graduate Institute of Medicine. Kaohsiung Medical University. Kaohsiung. TWN ;
School of Public Health. Kaohsiung Medical University. Kaohsiung. TWN
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Type de document :
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Article
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Dans :
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International journal of epidemiology (vol. 29, n° 2, 2000)
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Pagination :
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224-231
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Langues:
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Anglais
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Mots-clés :
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Cancer
;
Homme
;
Femme
;
Epidémiologie
;
Facteur risque
;
Tabagisme passif
;
Pollution atmosphérique
;
Appareil respiratoire [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST OR0xeABb. Diffusion soumise à autorisation]. Background For a female population with a high lung cancer mortality rate, such as Taiwanese women, who smoke relatively rarely, but live in an environment with high male smoking prevalence, the risk and population burden of lung cancer due to environmental tobacco smoke (ETS) are relatively important. Methods An age-matched case-control study was designed to investigate the effects of cumulative environmental exposure to tobacco smoke during childhood and adult life on lung cancer risk among non-smoking women in Taiwan. Information on passive smoking from all possible sources and life periods were obtained from interviews with 268 and 445 lifetime non-smoking cases and controls. Conditional logistic regression and synergism'S'index were applied to the data to assess the independent and joint effects of passive smoking in different life stages while controlling for possible confounding variables. Results Risks of contracting lung cancer among women near-distantly exposed to the highest level of ETS in childhood (>20 smoker-years) and in adult life (>40 smoker-years) were 1.8-fold (95% CI : 1.2-2.9) and 2.2-fold (95% CI : 1.4-3.7) higher than that among women being never exposed to ETS, and the two variables accounted for about 37% of tumours in this non-smoking female population. (...)
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