Résumé :
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[BDSP. Notice produite par INIST-CNRS R0x9pXgT. Diffusion soumise à autorisation]. Numerous studies have examined the association between coffee consumption and risk of myocardial infarction (Ml), but results have been inconsistent. Case-control studies generally suggest a harmful effect of coffee drinking, whereas cohort studies have mostly shown no association. Recent studies found that coffee may lower the risk of diabetes, a major coronary risk factor. The authors prospectively examined the effect of coffee consumption on Ml risk in 32,650 older Swedish women, aged 40-74 years, participating in the Swedish Mammography Cohort ; 459 cases of Ml developed during 165,896 person-years of follow-up from 1997 to 2002. After adjustment for age, coronary heart disease risk factors, and dietary variables, the relative risk of Ml associated with drinking>5 cups/week versus 0-4 cups/week was 0.68 (95% confidence interval (Cl) : 0.43,1.07). The authors observed a nonsignificant trend toward lower risk with higher consumption levels. Compared with that for 0-4 cups/week, the relative risks of Ml were 0.84 (95% Cl : 0.51,1.38) for 5-7 cups/week, 0.65 (95% Cl : 0.41,1.03) for 2-3 cups/day, 0.64 (95% Cl : 0.39,1.04) for 4-5 cups/day, and 0.65 (95% Cl : 0.37,1.12) for>6 cups/day (p-trend=0.07). Contrary to previous case-control studies, the authors concluded that coffee consumption does not increase Ml risk. Coffee consumption of>5 cups/week was nonsignificantly inversely associated with Ml risk among older Swedish women.
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