Titre :
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Trends in causes of death in the Aquitaine cohort of hiv-infected patients, 1995-1997. (2001)
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Auteurs :
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Stéphanie Vandentorren ;
Francois Dabis ;
S. FARBOS ;
D. MALVY ;
C. MARIMOUTOU ;
P. MERCIE ;
D. NEAU ;
Centre d'Information et de Soins de l'Immunodéficience Humaine Cisih Chu. Bordeaux. FRA ;
Groupe d'Epidémiologie Clinique du Sida en Aquitaine Gecsa. FRA ;
Inserm U330. Bordeaux. FRA
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Type de document :
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Article
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Dans :
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European journal of epidemiology (vol. 17, n° 1, 2001)
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Pagination :
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7-10
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Langues:
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Anglais
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Mots-clés :
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Mortalité
;
Mort
;
Sida
;
Virose
;
Infection
;
VIH
;
Rétrovirus
;
Virus
;
Epidémiologie
;
Evolution
;
Homme
;
France
;
Europe
;
Immunopathologie
;
Facteur
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Résumé :
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[BDSP. Notice produite par INIST-CNRS yvR0xleG. Diffusion soumise à autorisation]. Objective : To describe trends in the evolution of causes of death in a cohort of HIV-infected patients before and after the introduction of highly active antiretroviral treatment (HAART). Methods : This descriptive study concerned all the patients of the Aquitaine cohort who died between 1995 and 1997. Causes of deaths were grouped into 13 deaths due to an AIDS-defining underlying cause'and eight'non AIDS'categories. Comparisons were performed between two comparable periods of 18 months, January 1995-June 1996 and July 1996-December 1997 to focus on changes introduced by the prescription of HAART in June 1996. Results : Five hundred and thirty-two deaths were notified in 36 months for a total of 3687 patients. The comparison between causes of deaths before and after June 1996 showed a significant difference between the two periods with a decreasing proportion of AIDS causes of death, from 82.7% to 72.2% (p=0.007). Conclusion : HAART treatment has reduced the number and percentage of deaths due to AIDS-related causes among persons who died with HIV infection in South-western France.
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