Titre :
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Selection by indication of potent antiretroviral therapy use in a large cohort of women infected with human immunodeficiency virus. (2000)
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Auteurs :
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L. AHDIEH ;
K. ANASTOS ;
M. COHEN ;
S.J. GANGE ;
R. GREENBLATT ;
A. KOVACS ;
H. MINKOFF ;
A. MUNOZ ;
M. NOWICKI ;
M. YOUNG ;
Department of Epidemiology. School of Hygiene and Public Health. The Johns Hopkins University. Baltimore. MD. USA
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Type de document :
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Article
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Dans :
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American journal of epidemiology (vol. 152, n° 10, 2000)
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Pagination :
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923-933
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Langues:
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Anglais
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Mots-clés :
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Sida
;
Virose
;
Infection
;
VIH
;
Rétrovirus
;
Virus
;
Médicament antiviral
;
Thérapeutique médicamenteuse
;
Thérapeutique
;
Epidémiologie
;
Homme
;
Femme
;
Immunopathologie
;
Biais sélection
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Résumé :
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[BDSP. Notice produite par INIST A30R0xyC. Diffusion soumise à autorisation]. To characterize selection factors related to therapy initiation, the authors investigated the extent to which key markers of human immunodeficiency virus (HIV) disease severity were associated with initiation of potent antiretroviral therapy (ART). Logistic regression was used to determine the effects of CD4+cell count and HIV RNA level on potent ART initiation during 6-month periods among 2,059 HIV-infected US women enrolled in the Women's Interagency HIV Study. Low CD4+counts and high HIV RNA levels were significantly (p
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