Titre : | Carriage of serogroup W-135, ET-37 meningococci in The Gambia : Implications for immunisation policy ? (2000) |
Auteurs : | Jenny-M MACLENNAN ; Brian GREENWOOD ; David GRIFFITHS ; Martin-Cj MAIDEN ; Steven OBARO ; Rachel URWIN ; Department of Infectious and Tropical Diseases. London School of Hygiene and Tropical Medicine. London. GBR ; Medical Research Council Laboratories. Fajara Banjul. GMB ; Oxford Vaccine Group. Department of Paedlatrlcs. University of Oxford. John Radcliffe Hospital. Oxford. GBR |
Type de document : | Article |
Dans : | Lancet (The) (vol. 356, n° 9235, 2000) |
Pagination : | 1078- |
Langues: | Anglais |
Mots-clés : | Bactériose ; Infection ; Bactérie ; Gambie ; Afrique ; Epidémiologie ; Homme |
Résumé : | [BDSP. Notice produite par INIST 5TjXR0x5. Diffusion soumise à autorisation]. We found high levels of symptomless carriage of a hyperinvasive Nelsserla meningitldis strain (electrophoretic type 37 [ET-37], serogroup W-135) during a vaccine trial in Gamblan children In 1996. Serogroup C, ET-37 complex meningococci cause 30-40% of meningococcal disease in countries such as the UK, and have a point prevalence of 0.5-1.0%. The recent Haj-associated spread of serogroup W-135, ET-37 complex meningococci, which has been accompanied by numerous secondary cases, might be explained by the apparently raised carriage rates reported here. |