Titre :
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Lifelong teetotallers, ex-drinkers and drinkers : Mortality and the incidence of major coronary heart disease events in middle-aged British men. (1997)
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Auteurs :
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S.G. WANNAMETHEE ;
A.G. SHAPER ;
Division of Research. Kaiser Permanente Medical Care Program. Northern California Region. Oakland. CA. USA
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Type de document :
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Article
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Dans :
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International journal of epidemiology (vol. 26, n° 3, 1997)
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Pagination :
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523-531
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Langues:
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Anglais
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Mots-clés :
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Consommation
;
Boisson alcoolisée
;
Abstinence
;
Cardiopathie coronaire
;
Mortalité
;
Epidémiologie
;
Incidence
;
Facteur risque
;
Homme
;
Royaume Uni
;
Europe
;
Etude comparée
;
Appareil circulatoire [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST ByR0xnJg. Diffusion soumise à autorisation]. Background. To determine the risk of all cause mortality and the incidence of major coronary heart disease (CHD) events in lifelong teetotallers and in ex-drinkers compared with occasional and regular drinkers. Methods. A prospective study of middle-aged men drawn at random from one general practice in each of 24 British towns. Five years after the screening of 7735 men aged 40-59 years, 7167 provided further information on postal questionnaire enabling separation of non-drinkers into lifelong teetotallers and ex-drinkers. Results. During the follow-up period of 9.8 years after the postal questionnaire there were 929 deaths from all causes and 490 major CHD events. Ex-drinkers exhibited increased cardiovascular and non-cardiovascular mortality ; lifelong teetotallers showed the lowest cardiovascular mortality but a significantly increased non-cardiovascular mortality. After adjustment for confounding factors and pre-existing disease, the two non-drinking groups did not differ significantly in all cause mortality from occasional and regular drinkers (light, moderate or heavy) but lifelong teetotallers still showed a significant increase in non-cardiovascular mortality. Adjustment considerably attenuated the risk of both cardiovascular and non-cardiovascular mortality in the ex-drinkers. (...)
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