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MCKEOWN-EYSSEN (Gail) : CAN. Department of Nutritional Sciences. University of Toronto. ; Cornelia BAINES ; COLE (David-Ec) : CAN. Department of Laboratory Medicine and Pathology. University of Toronto. ; Vartouhi JAZMAJI ; MARSHALL (Lynn) : CAN. Environmental Health Clinic Unit. Women's College Hospital Toronto. ; RILEY (Nicole) : CAN. Centre for Addiction and Mental Health. ; TYNDALE (Rachel-F) : CAN. Department of Pharmacology. University of Toronto. ; University of Toronto. Department of Public Health Sciences. Toronto. CAN |[BDSP. Notice produite par INIST-CNRS wu4WR0xF. Diffusion soumise à autorisation]. Background : Impaired metabolism of toxic chemicals is a postulated mechanism underlying multiple chemical sensitivity (MCS). Because genetic variation alters the[...]Article
L. SHARP ; A.H. CARDY ; S.C. COTTON ; J. LITTLE ; Epidemiology Group. Department of Medicine and Therapeutics. University of Aberdeen. Aberdeen. GBR |[BDSP. Notice produite par INIST-CNRS D6R0xWjV. Diffusion soumise à autorisation]. The cytochrome P-450c17alpha (CYP17) gene, located on chromosome 10q24.3, encodes the enzyme cytochrome P-450c17alpha, which functions at key branch points in ste[...]Article
Martha-L SLATTERY ; T.R. Levin ; K. MA ; M. MURTAUGH ; S. NEUHAUSEN ; W. SAMOWTIZ ; C. SWEENEY ; University of Utah Health Sciences Center. Health Research Center. Salt Lake City. UT. USA |[BDSP. Notice produite par INIST-CNRS 4drR0xsf. Diffusion soumise à autorisation]. Cytochrome P-450 (CYP) is involved in the activation and metabolism of polycyclic aromatic hydrocarbons in tobacco products. The authors evaluated the association[...]Article
Channa KESHAVA ; MCCANLIES (Erin-C) : USA. Biostatistics and Epidemiology Branch. Health Effects Laboratory Division. National Institute for Occupational Safety and Health. Centers for Disease Control and Prevention. Morgantown. WV. ; Ainsley WESTON ; Centers for Disease Control and Prevention. National Institute for Occupational Safety and Health. Toxicology and Molecular Biology Branch. Molecular Epidemiology Team. Morgantown. WV. USA |[BDSP. Notice produite par INIST-CNRS JR0xTLrP. Diffusion soumise à autorisation]. The steroid hydroxylase CYP3A4 is the most abundant P-450 enzyme in the human liver, and CYP3A enzymes metabolize more than 50% of prescription drugs. The CYP3A4 [...]Article
Lenore-J LAUNER ; Claudine Berr ; Alain FAVIER ; Catherine GARREL ; Véronique GOURLET ; Marie-Jeanne Richard ; Hôpital La Colombiere. Inserm E0361. Pathologies du système nerveux. Recherche clinique et épidémiologique. Montpellier. FRA ; National Institutes of Health. National Institute on Aging. Laboratory of Epidemiology Demography and Biometry. Bethesda. MD. USA |[BDSP. Notice produite par INIST-CNRS SR0xTK90. Diffusion soumise à autorisation]. We studied whether primary enzymatic antioxidant protection should influence cognitive decline (CD) in subjects aged 62-72 years volunteers in the Etude du Vieill[...]Article
Christos NTAIS ; IOANNIDIS (John-Pa) : GRC. Biomedical Research Institute. Foundation for Research and Technology-Hellas. Ioannina. ; Anastasia POLYCARPOU ; University of loannina School of Medicine. Department of Hygiene and Epidemiology. Clinical and Molecular Epidemiology Unit. Ioannina. GRC |[BDSP. Notice produite par INIST-CNRS 95iR0xKt. Diffusion soumise à autorisation]. A C-to-T polymorphism in exon 2 of the cathepsin D gene encoding cathepsin D (CTSD) has been implicated as a risk factor for Alzheimer's disease. The authors perf[...]Article
Marco ZAFFANELLO ; Rossella GAUDINO ; Simone RUGOLOTTO ; Luciano TATO ; Giorgio ZAMBONI ; University of Verona. Department of Paediatrics. Verona. ITA ; University of Verona. Regional Centre of Neonatal Screening for Inborn Errors of Metabolism. Verona. ITA |[BDSP. Notice produite par INIST-CNRS 5E4TR0xM. Diffusion soumise à autorisation]. We examined glucose-6-phosphate dehydrogenase (G6PD) deficiency in north-eastern Italian Caucasian neonates detected by neonatal screening, in order to measure th[...]Article
Stanislas Pol ; Jeanne SERPAGCI ; Hôpital Necker. Inserm. U-370. Paris. FRA ; Hôpital Necker. Service d'Hépatologie. Paris. FRA |[BDSP. Notice produite par INIST-CNRS 9R0xD9qU. Diffusion soumise à autorisation]. Les infections par le virus de l'hépatite C (VHC) exposent principalement à un risque d'hépatite chronique pouvant justifier des traitements dont les progrès ont [...]Article
Linda SHARP ; Julian LITTLE ; University of Aberdeen. Department of Medicine and Therapeutics. Epidemiology Group. Aberdeen Scotland. GBR |[BDSP. Notice produite par INIST-CNRS tR0xtWKL. Diffusion soumise à autorisation]. Epidemiologic and mechanistic evidence suggests that folate is involved in colorectal neoplasia. Some polymorphic genes involved in folate metabolism-methylenetet[...]Article
Paul BRENNAN ; Douglas-A BELL ; Simone Benhamou ; Paolo BOFFETTA ; Christine BOUCHARDY ; Neil CAPORASO ; . CHU CHEN ; Christiane COUTELLE ; Scott-R DIEHL ; Mia HASHIBE ; Richard-B HAYES ; Sarah LEWIS ; Andrew-F OLSHAN ; Stephen-M SCHWARTZ ; Erich-M STURGIS ; Qingyi WEI ; Athanasios-I ZAVRAS ; University of Texas M D Anderson Cancer Center. Department of Epidemiology. Houston. TX. USA ; University of Texas M D Anderson Cancer Center. Department of Head and Neck Surgery. Houston. TX. USA |[BDSP. Notice produite par INIST-CNRS G0R0xR6W. Diffusion soumise à autorisation]. Possession of the fast metabolizing alleles for alcohol dehydrogenase (ADH), ADH1B*2 and ADH1C*1, and the null allele for aldehyde dehydrogenase (ALDH), ALDH2*2, [...]Article
Luis-Alberto GARCIA RODRIGUEZ ; HERNANDEZ-DIAZ (Sonia) : USA. Slone Epidemiology Center. Boston University. Boston. MA. |[BDSP. Notice produite par INIST-CNRS R0xMa26V. Diffusion soumise à autorisation]. The association between nonsteroidal antiinflammatory drugs (NSAIDs) and upper gastrointestinal complications is well documented. However, epidemiologic data on t[...]Article
. YAWEI ZHANG ; . BING ZHANG ; Peter BOYLE ; Theodore-R HOLFORD ; . HONG XIE ; . KAIYONG ZOU ; Patricia-H OWENS ; Jennifer RUSIECKI ; . TONGZHANG ZHENG ; John-Piece WISE ; . YONG ZHU ; Shelia-Hoar ZAHM ; University of Southern Maine. School of Applied Science Engineering and Technology. Department of Applied Medical Sciences. Portland. ME. USA ; Yale University. School of Medicine. Department of Epidemiology and Public Health. New Haven. CT. USA |[BDSP. Notice produite par INIST-CNRS uQQFR0xt. Diffusion soumise à autorisation]. Recent epidemiologic studies have suggested that genetic polymorphisms in the cytochrome P-450 1A1 gene (CYP1A1) may affect the relation between environmental exp[...]Article
Jean-Louis CHIASSON ; Ramon GOMIS ; Markolf HANEFELD ; Robert-G Josse ; Avraham KARASIK ; Markku LAAKSO ; Stop-Niddm Trial Research Group. INC |[BDSP. Notice produite par INIST-CNRS dR0xw9ri. Diffusion soumise à autorisation]. Context : The worldwide explosive increase in type 2 diabetes mellitus and its cardiovascular morbidity are becoming major health concerns. Objective To evaluate [...]Article
Loretta-D SPOTILA ; Karla-V BALLMAN ; Peter-B Berger ; Rcurtis ELLISON ; Paul-F JACQUES ; Rima ROZEN |[BDSP. Notice produite par INIST-CNRS 7mTkLR0x. Diffusion soumise à autorisation]. An elevated plasma homocysteine level is a risk factor for cardiovascular disease and is often observed in other common disorders, including neural tube defects, [...]Article
[BDSP. Notice produite par INIST-CNRS ZR0x6KEt. Diffusion soumise à autorisation]. We examined co-occurrence of (comorbid) alcohol, drug, and non-substance use psychiatric disorders in a population sample of Mexican-origin adults from rural and [...]