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Auteur J. LITTLE |
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E. TAIOLI ; Y.O. AHN ; D.T. BISHOP ; J. BOST ; B. BUDAI ; K. CHEN ; M.A. GARZA ; F. GEMIGNANI ; T. KEKU ; L. LE MARCHAND ; C.S.P. LIMA ; J. LITTLE ; K. MATSUO ; C.G. MOORE ; V. MORENO ; J. PLASCHKE ; M. PUFULETE ; S.B. Thomas ; G. TOFFOLI ; C.R. WOLF ; Graduate School of Public Health and Department of Medicine. Division of General Internal Medicine. University of Pittsburgh Medical Center. University of Pittsburgh. Pittsburgh. PA. USA ; Suny Downstate Medical Center. Brooklyn. NY. USA |[BDSP. Notice produite par INIST-CNRS IR0xIqtE. Diffusion soumise à autorisation]. Worldwide, over 1 million cases of colorectal cancer (CRC) were reported in 2002, with a 50% mortality rate, making CRC the second most common cancer in adults. C[...]Article
L.F. Masson ; S.C. COTTON ; J. LITTLE ; L. SHARP ; University of Aberdeen. Department of Public Health. Epidemiology Group. Aberdeen. GBR |[BDSP. Notice produite par INIST-CNRS JR0xO1Ix. Diffusion soumise à autorisation]. Cytochrome P-450 (CYP) 1A1 plays a key role in phase I metabolism of polycyclic aromatic hydrocarbons and in estrogen metabolism. It is expressed predominantly in[...]Article
L. SHARP ; A.H. CARDY ; S.C. COTTON ; J. LITTLE ; Epidemiology Group. Department of Medicine and Therapeutics. University of Aberdeen. Aberdeen. GBR |[BDSP. Notice produite par INIST-CNRS D6R0xWjV. Diffusion soumise à autorisation]. The cytochrome P-450c17alpha (CYP17) gene, located on chromosome 10q24.3, encodes the enzyme cytochrome P-450c17alpha, which functions at key branch points in ste[...]Article
S.C. COTTON ; N. BROCKTON ; J. LITTLE ; L. SHARP ; Epidemiology Group. Department of Medicine and Therapeutics. Faculty of Medicine and Medical Sciences. University of Aberdeen. Foresterhill House Annex. Foresterhill. Aberdeen Scotland. GBR |[BDSP. Notice produite par INIST ALR0xGeU. Diffusion soumise à autorisation]. The genes glutathione S-transferase M1 (GSTM1) (chromosome 1p13.3) and glutathione S-transferase T1 (GSTT1) (22q11.2) code for cytosolic enzymes glutathione S-transfer[...]Article
N. BROCKTON ; S.C. COTTON ; J. LITTLE ; L. SHARP ; Epidemiology Group. Department of Medicine and Therapeutics. University of Aberdeen. Foresterhill House Annex. Foresterhill. Aberdeen Scotland. GBR |[BDSP. Notice produite par INIST 1R0x2p25. Diffusion soumise à autorisation]. The two expressed genes coding for N-acetyltransferase (NAT) activity, NAT1 and NAT2, are located on chromosome 8 at 8p21.3-23.1 and are polymorphic. Both enzymes are [...]Article
S. PRESTON-MARTIN ; A. ARSLAN ; M. BLETTNER ; N.W. CHOI ; G.G. GILES ; G.R. HOWE ; J. LITTLE ; F. MENEGOZ ; J.M. POGODA ; Y. RODVALL ; P. RYAN ; B. SCHLEHOFER ; German Cancer Research Centre. Heidelberg. DEU |[BDSP. Notice produite par INIST pzhkeR0x. Diffusion soumise à autorisation]. Background Increased brain tumour risk after head trauma suggested by case reports and clinical series has been previously studied epidemiologically with mixed results[...]