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Tauseef-A KHAN ; Mohammad-R ABDOLLAHI ; Yoav BEN-SHLOMO ; Juan-P Casas ; Jackie COOPER ; Ian DAY ; John DEANFIELD ; Ann DONALD ; Shah EBRAHIM ; Luigi FERRUCCI ; Gerda FILLENBAUM ; Gerald-R FOWKES ; Ruth FRIKKE-SCHMIDT ; Tom-R GAUNT ; Grazyna GROMADZKA ; John Hardy ; Bastiaan-T HEIJMANS ; Aroon-D HINGORANI ; Jaroslav-A HUBACEK ; Steve-E HUMPHRIES ; . KAI SUN ; Tomohiro KATSUYA ; Kay-Tee KHAW ; Mika KIVIMAKI ; Meena KUMARI ; Debbie-A LAWLOR ; Mar MATARIN ; James MESCHIA ; Richard MORRIS ; Michael NAILS ; Jackie PRICE ; David PRIETO ; Stephen-S RICH ; . RUTAI HUI ; Manjinder SANDHU ; Tina SHAH ; Andrew SINGLETON ; Arjen-Jc SLOOTER ; Liam SMEETH ; George-Davey Smith ; Johan SUNDSTROM ; Zoltan SZOLNOKI ; Philippa-J TALMUD ; Anne TYBJAERG-HANSEN ; Nicholas WAREHAM ; . WEILI ZHANG ; Peter WHINCUP ; John WHITTAKER ; Bradford WORRALL |[BDSP. Notice produite par INIST-CNRS IDR0xEsI. Diffusion soumise à autorisation]. Background At the APOE gene, encoding apolipoprotein E, genotypes of the epsilon2/epsilon3/epsilon4 alleles associated with higher LDL-cholesterol (LDL-C) levels [...]Article
Gie KEN-DROR ; Fotios DRENOS ; Steve-E HUMPHRIES ; Mika KIVIMAKI ; Meena KUMARI ; Centre for Cardiovascular Genetics. Bhf Laboratories. The Rayne Building. Department of Medicine. Royal Free and University College Medical School. London. GBR |[BDSP. Notice produite par INIST-CNRS CIHGER0x. Diffusion soumise à autorisation]. Mendelian randomization studies on fibrinogen commonly use a single genetic variant as an instrument, but this may explain only a small proportion of the total ph[...]Article
Gie KEN-DROR ; Jackie-A COOPER ; Fotios DRENOS ; Steve-E HUMPHRIES ; IRELAND (Helen-A) : GBR. Northwick Park Institute for Medical Research. Harrow Middlesex. ; Centre for Cardiovascular Genetics. Bhf Laboratories. Department of Medicine. Royal Free and University College Medical School. University of London. London. GBR |[BDSP. Notice produite par INIST-CNRS 7mR0xDtq. Diffusion soumise à autorisation]. Plasma protein S (PS) levels are reportedly low in patients with venous thrombosis but high in coronary heart disease (CHD) patients. The authors examined the ass[...]Article
Tina SHAH ; Juan-P Casas ; Jackie-A COOPER ; John-E DEANFIELD ; Fgerald-R FOWKES ; Aroon-D HINGORANI ; Steve-E HUMPHRIES ; Gordon-D LOWE ; Valerie MCCORMACK ; Ann RUMLEY ; Liam SMEETH ; Reecha SOFAT ; Ioanna TZOULAKI ; Centre for Clinical Pharmacology. University College London. London. GBR |[BDSP. Notice produite par INIST-CNRS 9R0x78H8. Diffusion soumise à autorisation]. Background : Non-uniform reporting of relevant relationships and metrics hampers critical appraisal of the clinical utility of C-reactive protein (CRP) measuremen[...]Article
Juan-P Casas ; Leonelo-E BAUTISTA ; Helen-M COLHOUN ; Jackie COOPER ; Giovanni DI MINNO ; Dairena GAFFNEY ; Anders HAMSTEN ; Emma HAWE ; Aroon-D HINGORANI ; Steve-E HUMPHRIES ; Steven-J HUREL ; Irene JUHAN-VAGUE ; Teake KOOISTRA ; Shona LIVINGSTONE ; Maurizio MARGAGLIONE ; Alex-D MCMAHON ; Tom MEADE ; George-J MILLER ; Denis-S O'REILLY ; Christopher-J PACKARD ; Naveed SATTAR ; Tina SHAH ; Jeffrey-W STEPHENS ; Elena TREMOLI ; John-S YUDKIN ; Glasgow Royal Infirmary. Department of Pathological Biochemistry. Glasgow. GBR ; Ospedale Casa Sollievo della Sofferenza. Instituto di Ricovero e Cura a Carattere Scientifico. San Giovanni Rotondo. ITA ; University College London. (U.C.L.). Bhf Laboratories. Department of Medicine. Centre for Cardiovascular Genetics. London. GBR ; University College London. (U.C.L.). Bhf Laboratories. Department of Medicine. Centre for Clinical Pharmacology. London. GBR ; University College London. (U.C.L.). Department of Epidemiology. London. GBR |[BDSP. Notice produite par INIST-CNRS R0xk1D4Q. Diffusion soumise à autorisation]. Background : It is unclear wheather the association between C-reactive protein (CRP) and incident coronary events is free from bias and confounding. Individuals h[...]Article
Melissa-A AUSTIN ; Steve-E HUMPHRIES ; Carolyn-M HUTTER ; Ron-L ZIMMERN ; University of Washington. Institute for Public Health Genetics. Seattle. WA. USA |[BDSP. Notice produite par INIST-CNRS TcR0xIyG. Diffusion soumise à autorisation]. Familial hypercholesterolemia (FH) is an autosomal disorder characterized by increased levels of total cholesterol and low density lipoprotein cholesterol. The FH[...]Article
Melissa-A AUSTIN ; Steve-E HUMPHRIES ; Carolyn-M HUTTER ; Ron-L ZIMMERN ; University of Washington. Institute for Public Health Genetics. Seattle. WA. USA |[BDSP. Notice produite par INIST-CNRS 5R0xPFF8. Diffusion soumise à autorisation]. The clinical phenotype of heterozygous familial hypercholesterolemia (FH) is characterized by increased plasma levels of total cholesterol and low density lipopro[...]
Article : Fascicule
Steve-E HUMPHRIES ; Manjeet BOLLA ; Ian-Nm DAY ; Emma HAWE ; George-J MILLER ; Philippa-J TALMUD ; Centre for Cardiovascular Genetics. Department of Medicine. Royal Free and University College London Medical School. Rayne Institute. London. GBR |[BDSP. Notice produite par INIST-CNRS a7njsR0x. Diffusion soumise à autorisation]. Background The common isoforms of apolipoprotein E (apoE), E2, E3, and E4, are important determinants of plasma lipid concentrations, and the e4 allele is associa[...]Article : Fascicule
Derek-G COOK ; Richard-W ATKINSON ; Francesco-P CAPPUCCIO ; Andrew CHITOLIE ; Steve-E HUMPHRIES ; Edna-R NAKANDAKARE ; Giuseppe-A SAGNELLA ; Paul-D WICKS ; Blood Pressure Unit. Department of Medicine. St George's Hospital Medical School. London. GBR ; Centre for Cardiovascular Genetics. University College School of Medicine. London. GBR ; Department of Public Health Sciences. St George's Hospital Medical School. London. GBR |[BDSP. Notice produite par INIST Z6R0xztN. Diffusion soumise à autorisation]. Fibrinogen is a cardiovascular risk factor, but little is known about levels in ethnic groups that differ in their cardiovascular risk. Fibrinogen was measured in 479 [...]
