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Auteur Stephen BURGESS |
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Stephen BURGESS ; Raquel GRANELL ; School of Social and Community Medicine, University of Bristol (Bristol, Royaume-uni) ; Tom-M PALMER ; Jonathan-Ac STERNE ; Vanessa DIDELEZ |[BDSP. Notice produite par INIST-CNRS R0x87CJ9. Diffusion soumise à autorisation]. A parameter in a statistical model is identified if its value can be uniquely determined from the distribution of the observable data. We consider the context of [...]Article
[BDSP. Notice produite par INIST-CNRS 8tGR0x9E. Diffusion soumise à autorisation]. Mendelian randomization (MR) is a method for estimating the causal relationship between an exposure and an outcome using a genetic factor as an instrumental varia[...]Article
Stephen BURGESS ; Simon-G THOMPSON ; Crp Chd Genetics Collaboration. INC ; Mrc Biostatistics Unit. Institute of Public Health. University Forvie Site. Rosinson Way. Cambridge (O.S.R.). GBR |[BDSP. Notice produite par INIST-CNRS pE8nR0xn. Diffusion soumise à autorisation]. Background Mendelian randomization is used to test and estimate the magnitude of a causal effect of a phenotype on an outcome by using genetic variants as instrum[...]Article
Stephen BURGESS ; Juan-P Casas ; LAWLOR (Debbie-A) : GBR. Medical Research Council Centre for Causal Analyses in Translational Epidemiology. School of Social and Community Medicine. University of Bristol. Bristol. ; Shaun SEAMAN ; THOMPSON (Simon-G) : GBR. Department of Public Health and Primary Care. University of Cambridge. Cambridge. ; Medical Research Council Biostatistics Unit. University of Cambridge. Cambridge. GBR |[BDSP. Notice produite par INIST-CNRS ICnR0xDI. Diffusion soumise à autorisation]. Mendelian randomization studies typically have low power. Where there are several valid candidate genetic instruments, precision can be gained by using all the in[...]