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Article
Michael WOLFSON ; Paul-R BURTON ; Vincent FERRETTI ; Isabel Fortier ; Bartha Maria Knoppers ; Philippe LAFLAMME ; Julian LITTLE ; John MACLEOD ; Nicholas MASCA ; Geoff ROWE ; Nuala-A SHEEHAN ; Martin-D TOBIN ; Susan-E WALLACE ; Centre of Genomics and Policy. Faculty of Medicine. Department of Human Genetics. McGill University. Montreal. PQ. CAN ; Departments of Health Sciences and Genetics. University of Leicester. Leicester. GBR ; Public Population Project in Genomics. Montreal. PQ. CAN |[BDSP. Notice produite par INIST-CNRS 999BnR0x. Diffusion soumise à autorisation]. Background Contemporary bioscience sometimes demands vast sample sizes and there is often then no choice but to synthesize data across several studies and to unde[...]
Article
Tom-M PALMER ; Paul-R BURTON ; Nuala-A SHEEHAN ; John-R THOMPSON ; Martin-D TOBIN ; Department of Health Sciences. University of Leicester. GBR ; Departments of Health Sciences and Genetics. University of Leicester. GBR |[BDSP. Notice produite par INIST-CNRS 7mB7DR0x. Diffusion soumise à autorisation]. Background : Mendelian randomization uses a carefully selected gene as an instrumental-variable (IV) to test or estimate an association between a phenotype and a [...]
Article
Martin-D TOBIN ; Peter BRAUND ; Paul-R BURTON ; Cother HAJAT ; Mika KAHONEN ; Terho LEHTIMAKI ; Rami LEHTINEN ; Peter-W MACFARLANE ; Gandre NG ; Tuomo NIEMINEN ; Nilesh-J SAMANI ; Maciej TOMASZEWSKI ; Jari VIIK ; Department of Cardiovascular Sciences. University of Leicester. Glenfield Hospital. GBR ; Department of Clinical Physiology. Tampere University Hospital and Medical School. University of Tampere. FIN ; Department of Genetics. University of Leicester. GBR ; Department of Health Sciences. University of Leicester. GBR |[BDSP. Notice produite par INIST-CNRS Dk79DR0x. Diffusion soumise à autorisation]. Background : A longer heart-rate corrected QT interval (QTc) is associated with increased risk of ventricular arrhythmias. Women have longer resting QTc and are m[...]
Article
Mary DIXON-WOODS ; ASHCROFT (Richard-E) : GBR. Queen Mary. University of London. ; Paul-R BURTON ; Clare-J JACKSON ; Joëlle Kivits ; Nilesh-J SAMANI ; Martin-D TOBIN |[BDSP. Notice produite par INIST-CNRS XsR0xHz5. Diffusion soumise à autorisation]. Although the need to obtain "informed" consent is institutionalised as a principle of ethical practice in research, there is persistent evidence that the meanings[...]
Article
Cosetta MINELLI ; Keith-R Abrams ; John-R THOMPSON ; Martin-D TOBIN ; University of Leicester. Leicester Medical School. Department of Health Sciences. Centre for Biostatistics and Genetic Epidemiology. Leicester. GBR |[BDSP. Notice produite par INIST-CNRS 6R0xo7Yx. Diffusion soumise à autorisation]. A natural randomization process, sometimes called Mendelian randomization, occurs at conception to determine a person's genotype. By combining information from ge[...]
Article
M.B. KATAN ; Paul BRENNAN ; Paul-R BURTON ; David-V CONTI ; Shah EBRAHIM ; Richard GRAY ; Bernard KEAVNEY ; Cosetta MINELLI ; George-Davey Smith ; Duncan-C Thomas ; John-R THOMPSON ; Martin-D TOBIN ; Keith WHEATLEY ; University of Birmingham Clinical Trials Unit. Birmingham. GBR ; University of Leicester. Department of Epidemiology and Public Health. Leicester. GBR ; University of Southern California. Department of Preventive Medicine. Los Angeles. CA. USA |[BDSP. Notice produite par INIST-CNRS ZGVR0xk9. Diffusion soumise à autorisation].
