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Article
Russell-E GLASGOW ; CHAMBERS (David) : USA. Division of Services and Interventions Research. National Institute of Mental Health. Bethesda. MD. ; HUNTER (Christine) : USA. Division of Diabetes. Endocrinology. And Metabolic Diseases. National Institute of Diabetes and Digestive and Kidney Diseases. Bethesda. MD. ; KAPLAN (Robert-M) : USA. Behavioral and Social Sciences Research. National Institutes of Health. Bethesda. MD. ; Muin-J KHOURY ; Cynthia VINSON |[BDSP. Notice produite par INIST-CNRS mJ9sR0xE. Diffusion soumise à autorisation]. To address the vast gap between current knowledge and practice in the area of dissemination and implementation research, we address terminology, provide examples [...]
Article
Paolo BOFFETTA ; Vincent-J COGLIANO ; Stephen-S HECHT ; John-P IOANNIDIS ; Muin-J KHOURY ; Julian LITTLE ; Daniela SEMINARA ; George-Davey Smith ; Duncan-C Thomas ; Paolo VINEIS ; Deborah-M WINN |[BDSP. Notice produite par INIST-CNRS R0xBmnnk. Diffusion soumise à autorisation]. We propose guidelines to evaluate the cumulative evidence of gene-environment (G x E) interactions in the causation of human cancer. Our approach has its roots in[...]
Article
Acecile-Jw JANSSENS ; Sara BEDROSIAN ; Paolo BOFFETTA ; Siobhan-M DOLAN ; Nicole DOWLING ; Isabel Fortier ; Andrew-N FREEDMAN ; Jeremy-M GRIMSHAW ; Jeffrey GULCHER ; Marta GWINN ; Mark-A HLATKY ; John-Pa IOANNIDIS ; Holly JANES ; Muin-J KHOURY ; Peter KRAFT ; Julian LITTLE ; Stephanie MELILLO ; Christopher-J O'DONNELL ; Michael-J PENCINA ; David RANSOHOFF ; Sheri-D SCHULLY ; Daniela SEMINARA ; Cornelia-M VAN DUIJN ; Deborah-M WINN ; Caroline-F WRIGHT ; Department of Epidemiology. Erasmus University Medical Center. CA Rotterdam. NLD ; Office of Public Health Genomics. Centers for Disease Control and Prevention. Atlanta GA. USA |[BDSP. Notice produite par INIST-CNRS R0xIJk8j. Diffusion soumise à autorisation]. The rapid and continuing progress in gene discovery for complex diseases is fuelling interest in the potential application of genetic risk models for clinical and[...]
Article
MOONESINGHE (Ramal) : USA. Office of Minority Health and Health Disparities. Centers for Disease Control and Prevention. Atlanta. GA. ; Man-Huei CHANG ; Nicole-F DOWLING ; Muin-J KHOURY ; Alastair J. Scott ; Ajay YESUPRIYA ; Cdc Nci Nhanes Iii Genomics Working Group. INC ; Office of Public Health Genomics. Centers for Disease Control and Prevention. Atlanta. GA. USA |[BDSP. Notice produite par INIST-CNRS DER0x8lp. Diffusion soumise à autorisation]. Testing for deviations from Hardy-Weinberg equilibrium is a widely recommended practice for population-based genetic association studies. However, current methods[...]
Article
. QUANHE YANG ; Muin-J KHOURY ; MOONESINGHE (Ramal) : USA. Office of Minority Health. Centers for Disease Control and Prevention. Atlanta. GA. ; . TIEBIN LIU ; Rodolfo VALDEZ |[BDSP. Notice produite par INIST-CNRS R0xtlpm8. Diffusion soumise à autorisation]. Family history is an independent risk factor for diabetes, but it is not clear how much adding family history to other known risk factors would improve detection [...]
Article
JUN LI (.) : USA. Division of Cancer Prevention and Control. National Center for Chronic Disease Prevention and Health Promotion. Centers for Disease Control and Prevention. Atlanta. GA. ; Ralph-J COATES ; Marta GWINN ; Muin-J KHOURY |[BDSP. Notice produite par INIST-CNRS 9qokR0xG. Diffusion soumise à autorisation]. Steroid 5-alpha-reductase type 2 (SRD5a2) is a critical enzyme in androgen metabolism. Two polymorphisms in the SRD5a2 gene, V89L (rs523349) and A49T (rs9282858),[...]
Article
Muin-J KHOURY ; Jonine-L BERNSTEIN ; Lars BERTRAM ; Paolo BOFFETTA ; Paul-R BURTON ; Adam-S BUTTERWORTH ; Harry CAMPBELL ; Stephen-J CHANOCK ; Anand CHOCKALINGAM ; Siobhan-M DOLAN ; Isabel Fortier ; Helena FURBERG ; Montserrat GARCIA-CLOSAS ; Marta GWINN ; Julian-Pt HIGGINS ; John-Pa IOANNIDIS ; Acecile-Jw JANSSENS ; Julian LITTLE ; Thomas-R O'BRIEN ; James OSTELL ; Ryan-P OWEN ; Roberta-A PAGON ; Timothy-R REBBECK ; Nathaniel ROTHMAN ; Daniela SEMINARA ; Paolo VINEIS ; . WEI YU ; Deborah-M WINN ; Molecular Epidemiology Unit. University of Cambridge. Cambridge. GBR ; Office of Public Health Genomics. National Center for Chronic Disease Prevention and Health Promotion. Centers for Disease Control and Prevention. Atlanta. GA. USA |[BDSP. Notice produite par INIST-CNRS 8kmBtR0x. Diffusion soumise à autorisation]. Genome-wide association studies (GWAS) have led to a rapid increase in available data on common genetic variants and phenotypes and numerous discoveries of new lo[...]
Article
Man-Huei CHANG ; Mary-A BUTLER ; Stephen-J CHANOCK ; Nicole-F DOWLING ; Margaret GALLAGHER ; Muin-J KHOURY ; Mary-Lou LINDEGREN ; Ramal MOONESINGHE ; Cynthia-A MOORE ; Renée-M NED ; Mary-R REICHLER ; Christopher-L SANDERS ; Robert WELCH ; Ajay YESUPRIYA ; Cdc Nci Nhanes 3 Genomics Working Group. USA ; National Center for Hiv Aids Viral Hepatitis Std and Tb Prevention. Centers for Disease Control and Prevention. Atlanta. GA. USA |[BDSP. Notice produite par INIST-CNRS R0x87C8B. Diffusion soumise à autorisation]. Population-based allele frequencies and genotype prevalence are important for measuring the contribution of genetic variation to human disease susceptibility, pro[...]
Article
GODDARD (Katrina-Ab) : USA. Department of Epidemiology and Biostatistics. Case Western Reserve University. Cleveland. OH. ; Ann ANNIS-EMEOTT ; Mary-Pat BLAND ; Michelle-L COOK ; Debra DUQUETTE ; EDWARDS (Karen-L) : USA. Department of Epidemiology. University of Washington. Seattle. ; Rebecca-T GILES ; Jenny JOHNSON ; Muin-J KHOURY ; Patrick-W LEE ; OEHLKE (Kristin) : USA. Health Promotion and Chronic Disease Division. Minnesota Department of Health. St Paul. ; Ann RAFFERTY ; Amy ZLOT ; Chronic Disease Genomics Program. Utah Department of Public Health. Salt Lake City. USA ; Oregon Genetics Program. Public Health Division. Oregon. USA |[BDSP. Notice produite par INIST-CNRS F88R0xor. Diffusion soumise à autorisation]. We conducted population-based surveys on direct-to-consumer nutrigenomic testing in Michigan, Oregon, and Utah as part of the 2006 Behavioral Risk Factor Surveill[...]
Article
Julian LITTLE ; Nick BIRKETT ; Barbara COHEN ; George DAVEY-SMITH ; Isabel Fortier ; Matthew FREEDMAN ; France Gagnon ; Jean GOLDING ; Jeremy GRIMSHAW ; . GUANG YONG ZOU ; Marta GWINN ; Julian-Pt HIGGINS ; Kim HUTCHINGS ; Claire INFANTE-RIVARD ; John-Pa IOANNIDIS ; Candice-Y JOHNSON ; Muin-J KHOURY ; Richard KING ; John MCLAUGHLIN ; David MOHER ; Andrew PATERSON ; Paul SCHEET ; Alex STEWART ; Valerie TAIT ; Cornelia VAN DUIJN ; Erik VON ELM ; George WELLS ; Miriam WIENS ; Robin-E WILLIAMSON ; Maja ZECEVIC ; Department of Epidemiology and Community Medicine. University of Ottawa. Ottawa. ON. CAN |[BDSP. Notice produite par INIST-CNRS 7JER0xrs. Diffusion soumise à autorisation]. Making sense of rapidly evolving evidence on genetic associations is crucial to making genuine advances in human genomics and the eventual integration of this inf[...]
Article
John-Pa IOANNIDIS ; David-J BALDING ; Paolo BOFFETTA ; Anand CHOKKALINGAM ; W. DANA FLANDERS ; Siobhan-M DOLAN ; Timothy-M FRAYLING, disc. ; Julian-Pt HIGGINS ; Muin-J KHOURY ; Julian LITTLE ; Mark-I MCCARTHY ; David-H MCDERMOTT ; Thomas-R O'BRIEN ; Grier-P PAGE ; Timothy-R REBBECK ; Daniela SEMINARA ; André-G UITTERLINDEN ; Paolo VINEIS ; Department of Epidemiology and Public Health. Imperial College. London. GBR |[BDSP. Notice produite par INIST-CNRS R0xNSqfj. Diffusion soumise à autorisation]. Established guidelines for causal inference in epidemiological studies may be inappropriate for genetic associations. A consensus process was used to develop guid[...]
Article
Muin-J KHOURY ; H. CAMPBELL, disc. ; Marta GWINN ; IOANNIDIS (John-Pa) : GRC. Department of Hygiene and Epidemiology University of loannina School of Medicine. Ioannina. ; LITTLE (Julian) : CAN. Canada Research Chair in Human Genome Epidemiology. Department of Epidemiology and Community Medicine. University of Ottawa. Ottawa. ; T. MANOLIO, disc. ; University of Edinburgh. Public Health Sciences. Division of Community Health Sdences. Edinburgh. GBR ; University of Ottawa. Centers for Disease Control and Prevention. Coordinating Center for Health Promotion. National Office of Public Health Genomics. Ottawa. CAN |[BDSP. Notice produite par INIST-CNRS 8VAGR0xZ. Diffusion soumise à autorisation]. Emerging technologies are allowing researchers to study hundreds of thousands of genetic variants simultaneously as risk factors for common complex diseases. Both[...]
Article
Turning the pump handle : Evolving methods for integrating the evidence on gene-disease association.
Julian-Pt HIGGINS ; Betsy ANAGNOSTELIS ; Molly-S BRAY ; Adam-S BUTTERWORTH ; John DANESH ; Carol DEZATEUX ; John-E GALLACHER ; Marta GWINN ; John-Pa IOANNIDIS ; Muin-J KHOURY ; Sarah-J LEWIS ; Julian LITTLE ; Teri-A MANOLIO ; Cosetta MINELLI ; Paul-D PHAROAH ; Georgia SALANTI ; Simon SANDERSON ; Liam SMEETH ; Lesley-A Smith ; Jonathan-A STERNE ; Emanuela TAIOLI ; John-R THOMPSON ; Simon-G THOMPSON ; Neil WALKER ; Ron-L ZIMMERN ; Department of Hygiene and Epidemiology. University of loannina School of Medicine. Ioannina. GRC ; Department of Public Health and Primary Care. University of Cambridge. Cambridge. GBR ; National Office of Public Health Genomics. Centers for Disease Control and Prevention. Atlanta. GA. USA |[BDSP. Notice produite par INIST-CNRS R0xhaa99. Diffusion soumise à autorisation].
Article
Tracking the epidemiology of human genes in the literature : The HuGE published literature database.
Bruce-K LIN ; Melinda CLYNE ; GOMEZ (Onnalee) : USA. Information Center. Coordinating Center for Health Information Systems. Centers for Disease Control and Prevention. Atlanta. GA. ; Marta GWINN ; Muin-J KHOURY ; WALSH (Matthew) : USA. Department of Population Health Sciences. University of Wisconsin. Madison. WI. ; . WEI YU |[BDSP. Notice produite par INIST-CNRS wVqMlR0x. Diffusion soumise à autorisation]. Completion of the human genome sequence has inspired a new wave of epidemiologic studies on the prevalence of gene variants and their associations with diseases i[...]
Article
Alfredo MORABIA ; Michael-C COSTANZA ; Robert DAVIS, disc. ; Marta GWINN, disc. ; Muin-J KHOURY, disc. ; Mary-Lou LINDEGREN, disc. ; Paula YOON, disc. ; Centers for Disease Control and Prevention. Coordinating Center for Health Promotion. Office of Genomics and Disease Prevention. Atlanta. GA. USA |[BDSP. Notice produite par INIST-CNRS 4YdOR0xS. Diffusion soumise à autorisation].
