| Titre : | Exposome Factors Associated with Multimorbidity in Older Adults: An Exploratory Cross-Sectional Analysis in the Longitudinal Ageing Study Amsterdam |
| Auteurs : | Diana Juanita Mora ; Ecole des hautes études en santé publique (EHESP) (Rennes, FRA) |
| Type de document : | Mémoire |
| Année de publication : | 2024 |
| Description : | 75p. / fig., tabl, gloss. |
| Langues: | Anglais |
| Classement : | MPH/ (Mémoires MPH à partir de 2024) |
| Mots-clés : | Santé environnementale ; Vieillissement population ; Personne âgée ; Risque environnemental ; Exposome ; Maladie associée ; Morbidité ; Prévalence ; Maladie non transmissible ; Pays Bas |
| Résumé : |
Background: Ageing populations and longer life expectancies strain healthcare systems due to the rising prevalence of noncommunicable diseases (NCDs) and multimorbidity. Understanding the influence of environmental factors on NCD prevalence is crucial. Objectives: The study employs the exposome framework to investigate how built, physico-chemical, and contextual sociodemographic environmental domains associate with NCDs and multimorbidity in older adults. It aims to explore these relationships while considering individual sociodemographic variables such as age, sex, education, and income, and to identify associations across different demographic groups.
Methods: Data from 1,465 older adults from the Longitudinal Ageing Study Amsterdam cohort, wave 2008-2009, matched with environmental data from the Dutch Geoscience and Health Cohort Consortium, were analyzed. Unordered multivariate multinomial regression analyses were conducted for each environmental domain and in a comprehensive model, adjusted for sociodemographic variables. Subsequent comprehensive sensitivity analyses were performed. Results: Descriptive statistics revealed an average age of 72.8 years, female predominance (55%) with an even distribution among education categories and the majority falling within the high household income group. Most respondents reported having two or more NCDs. Multivariate multinomial regression analyses showed an association of increased greenery density and lower odds of singular NCDs (OR: 0.51, 95% CI: 0.34 – 0.77), proximity to essential services like general practices trended with lower multimorbidity, reduced air pollutant exposure, and favorable conditions such as optimal temperatures and attractive destinations in reducing NCD prevalence, with individual sociodemographic factors playing a crucial role. Conclusion: This study emphasizes the importance of employing the exposome framework to comprehensively explore the relationship between environmental exposures and NCD prevalence among older adults. The findings provide insights for future research in similar contexts and inform urban planning and public health interventions aimed at reducing NCD prevalence to promote healthy ageing. |
| Diplôme : | Master MPH of public health |
| Plan de classement simplifié : | Master of Public Health - master international de Santé Publique (MPH) |
| En ligne : | https://documentation.ehesp.fr/memoires/2024/mph/diana_juanita_mora.pdf |
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