| Titre : | Evaluating the Impact of Cold Chain Deviations on the Risk of Hepatitis B Infection in Children: A Study Utilizing Fridge-Tag2® Temperature Monitors for the Hepatitis B Birth Dose Vaccine in Burkina Faso |
| Auteurs : | Fadumo Abdullahi ; Ecole des hautes études en santé publique (EHESP) (Rennes, FRA) |
| Type de document : | Mémoire |
| Année de publication : | 2024 |
| Description : | 34p. / fig. |
| Langues: | Anglais |
| Classement : | MPH/ (Mémoires MPH à partir de 2024) |
| Mots-clés : | Hépatite virale B ; Vaccin ; Température ; Chaîne froid ; Vaccination ; Naissance ; Nourrisson ; Mère ; Burkina Faso |
| Résumé : | Maintaining the recommended cold chain of 2-8°C for vaccine storage and transport is challenging, especially in resource-poor settings. Timely birth dose administration is crucial to prevent mother-to-child transmission of hepatitis B virus (HBV). The monovalent hepatitis B vaccine has demonstrated heat stability in in-vivo and in-vitro studies. However, the impact of out-of-cold chain storage on vaccine effectiveness and immunogenicity has not been evaluated in real-world decentralized settings in Africa. This study assessed real-world temperature exposures of the monovalent hepatitis B birth dose and the impact of temperature deviations on vaccine effectiveness and immunogenicity in Burkina Faso. (R.A.) |
| Diplôme : | Master MPH of public health |
| Plan de classement simplifié : | Master of Public Health - master international de Santé Publique (MPH) |
| En ligne : | https://documentation.ehesp.fr/memoires/2024/mph/fadumo_abdullahi.pdf |
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