| Titre : | Use of the test-negative design case control study for estimating influenza vaccine effectiveness (VE) and relative vaccine effectiveness (rVE) in Europe: a review of the literature and quantitative bias assessment |
| Auteurs : | Aung Pone Myint ; Ecole des hautes études en santé publique (EHESP) (Rennes, FRA) |
| Type de document : | Mémoire |
| Année de publication : | 2021 |
| Description : | 53p. / tabl., fig., ann. |
| Langues: | Anglais |
| Classement : | MPH21/ |
| Mots-clés : | Vaccin ; Grippe ; Efficacité ; Europe ; Revue de littérature ; Evaluation ; Biais ; Enquête cas témoin |
| Résumé : | Seasonal influenza is a vaccine-preventable illness taking more than 300,000 lives annually around the world. The test-negative design case-control study (TND) is a method to assess the effectiveness in real-world setting. Objectives are 1) to explore the use of TND in vaccine effectiveness (VE) studies and identify the biases, 2) to describe the potential biases and its impact on the TND relative vaccine effectiveness (rVE) studies, and 3) to analyze the impact of the biases and bias correction methods. Literature review on TND VE studies and systematic literature review on TND rVE studies were conducted. Health-seeking behaviour difference should still be expected in TND studies for influenza VE. In rVE, the cases and controls are more comparable. The study design is fairly resistant to information bias. However, caution is still needed for clinical criteria and seasonal definition of the study inclusion as very few cases were observed in these participants. |
| Diplôme : | Master MPH of public health |
| Plan de classement simplifié : | Master of Public Health - master international de Santé Public (MPH) |
| En ligne : | https://documentation.ehesp.fr/memoires/2021/mph/aung_pone_myint.pdf |
Exemplaires (1)
| Code-barres | Cote | Support | Localisation | Section | Disponibilité |
|---|---|---|---|---|---|
| 090341 | MPH21/0016 | Mémoire | Rennes | Magasin | Empruntable Disponible |
Documents numériques (1)
 mph/myint URL |