| Titre : | Development of an ecological approach to measure the hospital burden associated with the RSV in the elderly (people over 65 years old), in France from 2010 to 2018 |
| Auteurs : | Maud Tisné |
| Type de document : | Mémoire |
| Année de publication : | 2021 |
| Description : | 41p. / ann., tabl., graph. |
| Langues: | Anglais |
| Classement : | MPH21/ |
| Mots-clés : | Virus ; Grippe ; Personne âgée ; Hospitalisation ; Prise charge médicosociale ; Infection respiratoire ; France |
| Résumé : |
Background: Infectious diseases such as influenza, respiratory syncytal virus (RSV) infections and pneumonia are caused by the transmission of a virus or a bacterium. Most people infected by them have a mild form of the disease and require no medical intervention. But the people over 65-year-old can present severe complications due to their physical condition. Thus, these respiratory infections represent a heavy hospital burden in France. In addition, it is very difficult to diagnose and differentiate influenza and RSV complications and therefore to identify all affected patients during epidemic seasons. This is due to the common characteristics of the two viruses, the lack of systematic diagnosis of respiratory secretions and to the latency between infections and the onset of symptoms and complications. The hospital burden directly associated with influenza and RSV is therefore underestimated because it is based solely on hospitalizations or deaths for which influenza or RSV diagnoses are identified.
Objective: Our objective was to develop an ecological approach to measure the hospital burden associated with the RSV infection in the elderly (people over 65 years old), in France from 2010 to 2018. Method: Firstly, we presented descriptive statistics of influenza and RSV. Then we used a statistical model to measure the hospital burden of RSV regarding two categories of hospitalizations. On the one hand a category regrouping the majority of respiratory infections, on the other hand a category called extended RSV, including pneumonia and respiratory infections being consequences of RSV. In our model, we took into account the circulation of influenza, using data from the Sentinelles database. We used the Santé Publique France database for the RSV circulation, and the SNDS database for the hospitalizations. Results: Our results show a high incidence of RSV in people over 65 years old. The estimated RSV-associated hospitalizations for respiratory cause was equal to 261 321 and to 186 272 for the extended RSV category from 2010 to 2018. Moreover, our results show an increasing number of hospitalizations due to RSV over the study period in people older than 65 years old with a peak in 2017. Rsv-related hospitalizations also tend to increase with age. Conclusion: These results reflect the impact of RSV in the elderly and the need to set up a specific surveillance system to accurately assess the circulation of this virus in this population, and the development of a vaccine to prevent this disease being a real public health issue, especially as the population is ageing. |
| Diplôme : | Master MPH of public health |
| Plan de classement simplifié : | Master of Public Health - master international de Santé Public (MPH) |
| En ligne : | https://documentation.ehesp.fr/memoires/2021/mph/maud_tisne.pdf |
Exemplaires (1)
| Code-barres | Cote | Support | Localisation | Section | Disponibilité |
|---|---|---|---|---|---|
| 095686 | MPH21/0004 | Mémoire | Rennes | Magasin | Empruntable Disponible |
Documents numériques (1)
 https://documentation.ehesp.fr/memoires/2021/mph/maud_tisne.pdf URL |