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Titre :
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Assessing Mumps Outbreak Risk in Highly Vaccinated Populations Using Spatial Seroprevalence Data (2014)
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Auteurs :
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Steven Abrams ;
Faculty of Science, Hasselt University (Diepenbeek, Belgique) ;
Philippe BEUTELS ;
Faculty of Medicine and Health Sciences, Vaccine and Infectious Disease Institute Who Collaborating Centre University of Antwerp (Antwerp, Belgique) ;
Niel HENS
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Type de document :
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Article
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Dans :
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American journal of epidemiology (vol. 179, n° 8, avril 2014)
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Pagination :
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1006-1017
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Langues:
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Anglais
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Mots-clés :
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Evaluation
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Oreillons
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Epidémie
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Facteur risque
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Risque
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Population
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Epidémiologie
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Prévalence
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Sérologie
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Pathologie
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Reproduction
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Hypothèse
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Vaccin
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Prévention santé
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Virose
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Infection
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Couverture vaccinale
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Résumé :
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[BDSP. Notice produite par INIST-CNRS R0xEGCml. Diffusion soumise à autorisation]. Mumps is a potentially severe viral infection. The incidence of mumps has declined dramatically in high-income countries since the introduction of mumps antigen-containing vaccines. However, recent large outbreaks of mumps in highly vaccinated populations suggest waning of vaccine-induced immunity and primary vaccine failure. In this paper we present a simple method for identifying geographic regions with high outbreak potential, demonstrated using 2006 mumps seroprevalence data from Belgium and Belgian vaccination coverage data. Predictions of the outbreak potential in terms of the effective reproduction number in future years signal an increased risk of new mumps outbreaks. Literature reviews on serological information for both primary vaccine failure and waning immunity provide essential information for our predictions. Tailor-made additional vaccination campaigns would be valuable for decreasing local pockets of susceptibility, thereby reducing the risk of future large-scale mumps outbreaks.
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