| Titre : | Long-term Coffee Consumption in Relation to Fracture Risk and Bone Mineral Density in Women (2013) |
| Auteurs : | Helena HALLSTROM ; Department of Surgical Sciences, Uppsala University (Uppsala, Suède) ; Liisa BYBERG ; Risk and Benefit Assessment Department, National Food Agency (Uppsala, Suède) ; Anders GLYNN ; Eva-Warensjö LEMMING ; Alicja WOLK ; Karl MICHAELSSON |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 178, n° 6, Septembre 2013) |
| Pagination : | 898-909 |
| Langues: | Anglais |
| Mots-clés : | Fracture ; Ostéoporose ; Long terme ; Café ; Consommation ; Facteur risque ; Risque ; Femme ; Epidémiologie ; Homme ; Traumatisme |
| Résumé : | [BDSP. Notice produite par INIST-CNRS R0xnI9IH. Diffusion soumise à autorisation]. High consumption of coffee has been suggested to reduce the risk of some late-onset diseases and death but also to contribute to the development of osteoporotic fractures. Results of previous fracture studies have been inconsistent, and a comprehensive study is needed. The longitudinal population-based Swedish Mammography Cohort, including 61,433 women born in 1914-1948, was followed up from 1987 through 2008. Coffee consumption was assessed with repeated food frequency questionnaires. During follow-up, 14,738 women experienced fracture of any type, and 3,871 had a hip fracture. In a subcohort (n=5,022), bone density was measured and osteoporosis determined (n=1,012). After multivariable adjustment, there was no evidence of a higher rate of any fracture (hazard ratio per 200 mL coffee=0.99 ; 95% confidence interval : 0.98,1.00) or hip fracture (hazard ratio per 200 mL coffee=0.97,95% confidence interval : 0.95,1.00) with increasing coffee consumption. A high coffee intake (>=4 cups daily) versus a low intake (<1 cup daily) was associated with a 2% - 4% lower bone density, depending on site (P<0.001), but the odds ratio for osteoporosis was only 1.28 (95% confidence interval : 0.88,1.87). Thus, high coffee consumption was associated with a small reduction in bone density that did not translate into an increased risk of fracture. |
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