| Titre : | Cigarette Smoking, Passive Smoking, and Non-Hodgkin Lymphoma Risk : Evidence From the California Teachers Study. (2011) |
| Auteurs : | . YANI LU ; Leslie BERNSTEIN ; Ellen-T CHANG ; Christina-A CLARKE ; . HUIYAN MA ; Peggy REYNOLDS ; Jane SULLIVAN-HALLEY ; Sophia-S WANG |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 174, n° 5, 2011) |
| Pagination : | 563-573 |
| Langues: | Anglais |
| Mots-clés : | Tabagisme passif ; Facteur risque ; Risque ; Enseignant ; Tabac ; Pollution ; Epidémiologie ; Amérique ; Amérique du Nord ; Cancer |
| Résumé : | [BDSP. Notice produite par INIST-CNRS nlnR0xmJ. Diffusion soumise à autorisation]. Epidemiologic studies conducted to date have shown evidence of a causal relation between smoking and non-Hodgkin lymphoma (NHL) risk. However, previous studies did not account for passive smoking exposure in the never-smoking reference group. The California Teachers Study collected information about lifetime smoking and household passive smoking exposure in 1995 and about lifetime exposure to passive smoking in 3 settings (household, workplace, and social settings) in 1997-1998. Multivariable-adjusted relative risks and 95% confidence intervals were estimated by fitting Cox proportional hazards models with follow-up through 2007. Compared with never smokers, ever smokers had a 1.11-fold (95% confidence interval (CI) : 0.94,1.30) higher NHL risk that increased to a 1.22-fold (95% CI : 0.95,1.57) higher risk when women with household passive smoking were excluded from the reference category. Statistically significant dose responses were observed for lifetime cumulative smoking exposure (intensity and pack-years ; both P's for trend=0.02) when women with household passive smoking were excluded from the reference category. Among never smokers, NHL risk increased with increasing lifetime exposure to passive smoking (relative risk=1.51 (95% CI : 1.03,2.22) for>40 years vs.<5 years of passive smoking ; P for trend=0.03), particularly for follicular lymphoma (relative risk=2.89 (95% CI : 1.23,6.80) ; P for trend=0.01). The present study provides evidence that smoking and passive smoking may influence NHL etiology, particularly for follicular lymphoma. |
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