GEIRA : gene-environment and gene-gene interaction... Catalogue en ligne

Titre :	GEIRA : gene-environment and gene-gene interaction research application. (2011)
Auteurs :	. BO DING ; Lars ALFREDSSON ; Henrik KALLBERG ; Lars KLARESKOG ; Leonid PADYUKOV ; Rheumatology Unit. Department of Medicine. Karolinska Institutet. Stockholm. SWE
Type de document :	Article
Dans :	European journal of epidemiology (vol. 26, n° 7, 2011)
Pagination :	557-561
Langues:	Anglais
Mots-clés :	Santé environnementale ; Gène ; Génétique ; Programme ; Homme ; Epidémiologie
Résumé :	[BDSP. Notice produite par INIST-CNRS ss998R0x. Diffusion soumise à autorisation]. The GEIRA (Gene-Environment and Gene-Gene Interaction Research Application) algorithm and subsequent program is dedicated to genome-wide gene-environment and gene-gene interaction analysis. It implements concepts of both additive and multiplicative interaction as well as calculations based on dominant, recessive and co-dominant genetic models, respectively. Estimates of interactions are incorporated in a single table to make the output easily read. The algorithm is coded in both SAS and R. GEIRA is freely available to non-commercial users. Additional information, including user's manual and example datasets is available online at http :/www. epinet. se.

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