| Titre : | Inclusion of African Americans in Genetic Studies : What Is the Barrier ? (2011) |
| Auteurs : | Sarah-M Hartz ; Laura-J BIERUT ; Naomi BRESLAU ; Dorothy HATSUKAMI ; Eric-O JOHNSON ; Nancy-L SACCONE ; Department of Psychiatry. School of Medicine. Washington University. St Louis. MO. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 174, n° 3, 2011) |
| Pagination : | 336-344 |
| Langues: | Anglais |
| Mots-clés : | Homme ; Génétique ; Définition ; Accès soins ; Soins ; Consommateur soins ; Consommateur ; Participation ; Collecte information ; Association ; Epidémiologie |
| Résumé : | [BDSP. Notice produite par INIST-CNRS J9n9R0xI. Diffusion soumise à autorisation]. To facilitate an increase in the amount of data on minority subjects collected for genetic databases, the authors attempted to clarify barriers to African-American participation in genetic studies. They randomly sampled 78,072 subjects from the community (Missouri Family Registry, 2002-2007). Of these, 28,658 participated in a telephone screening interview, 3,179 were eligible to participate in the genetic study, and 1,919 participated in the genetic study. Response rates were examined in relation to the proportion of subjects in the area who were African-American according to US Census 2000 zip code demographic data. Compared with zip codes with fewer than 5% African Americans (average=2% African-American), zip codes with at least 60% African Americans (average=87% African-American) had higher proportions of subjects with an incorrect address or telephone number but lower proportions of subjects who did not answer the telephone and subjects who refused the telephone interview (P<0.0001). Based on reported race from the telephone screening, 71% of eligible African Americans and 57% of eligible European Americans participated in the genetic study (P<0.0001). The results of this study suggest that increasing the number of African Americans in genetic databases may be achieved by increasing efforts to locate and contact them. |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact