| Titre : | Overweight and Obesity Over the Adult Life Course and Incident Mobility Limitation in Older Adults : The Health, Aging and Body Composition Study. (2009) |
| Auteurs : | HOUSTON (Denise-K) : USA. Sticht Center on Aging. Department of Internal Medicine. Section on Gerontology and Geriatric Medicine. Wake Forest University School of Medicine. Winston Salem. NC. ; Tamara-B HARRIS ; . JINGZHONG DING ; . JUNG SUN LEE ; Stephen-B KRITCHEVSKY ; Michael-C NEVITT ; Barbara-J NICKLAS ; Susan-M RUBIN ; Frances-A TYLAVSKY ; Health Abc Study. INC |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 169, n° 8, 2009) |
| Pagination : | 927-936 |
| Langues: | Anglais |
| Mots-clés : | Obésité ; Poids corporel ; Adulte ; Incidence ; Personne âgée ; Vieillissement ; Epidémiologie ; Homme |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 7HqoR0x9. Diffusion soumise à autorisation]. Obesity in middle and old age predicts mobility limitation ; however, the cumulative effect of overweight and/or obesity over the adult life course is unknown. The association between overweight and/or obesity in young, middle, and late adulthood and its cumulative effect on incident mobility limitation was examined among community-dwelling US adults aged 70-79 years at baseline (1997-1998) in the Health, Aging and Body Composition Study (n=2,845). Body mass index was calculated by using recalled weight at ages 25 and 50 years and measured weight at ages 70-79 years. Mobility limitation (difficulty walking 1/4 mile (0.4 km) or climbing 10 steps) was assessed semiannually over 7 years of follow-up and was reported by 43.0% of men and 53.7% of women. Men and women who were overweight or obese at all 3 time points had an increased risk of mobility limitation (hazard ratio=1.61,95% confidence interval : 1.25,2.06 and hazard ratio=2.85,95% confidence interval : 2.15,3.78, respectively) compared with those who were normal weight throughout. Furthermore, there was a significant graded response (P<0.0001) on risk of mobility limitation for the cumulative effect of obesity in men and overweight and/or obesity in women. Onset of overweight and obesity in earlier life contributes to an increased risk of mobility limitation in old age. |
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