| Titre : | China's AIDS Policy Implementation. Quality assurance in the HIV/AIDS laboratory network of China. (2010) |
| Auteurs : | . YAN JIANG ; Roger Detels, éd. ; . GUIYUN ZHANG ; . JUN YAO ; . MAOFENG QIU ; Chin-Yih OU ; . PINLIANG PAN ; Mary-Jane ROTHERAM-BORUS, éd. ; Y.U. WANG, éd. ; . WENGE XING ; Zunyou WU, éd. ; . XUELI SU ; . YAO XIAO ; National Hiv Hcv Reference Laboratory. National Center for Aids Std Control and Prevention. Chinese Center for Disease Control and Prevention. Beijing. CHN |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 39, n° 2, 2010) |
| Pagination : | ii72-ii78 |
| Langues: | Anglais |
| Mots-clés : | Sida ; Laboratoire ; Homme ; Chine ; Contrôle qualité ; Dépistage ; VIH ; Virose ; Infection ; Asie ; Rétrovirus ; Virus ; Immunopathologie |
| Résumé : | [BDSP. Notice produite par INIST-CNRS IHonpR0x. Diffusion soumise à autorisation]. Background In 2009, there were 8273 local screening laboratories, 254 confirmatory laboratories, 35 provincial confirmatory central laboratories and 1 National AIDS Reference Laboratory (NARL) in China. These laboratories were located in Center for Disease Control and Prevention (CDC) facilities, hospitals, blood donation clinics, maternal and child health (MCH) hospitals and border health quarantine health-care facilities. Methods The NARL and provincial laboratories provide quality assurance through technical, bio-safety and managerial training ; periodic proficiency testing ; on-site supervisory inspections ; and commercial serologic kit evaluations. Results From 2002 to 2009, more than 220 million HIV antibody tests were performed at screening laboratories, and all reactive and indeterminate samples were confirmed at confirmatory laboratories. The use of highly technically complex tests, including CD4 cell enumeration, viral load, dried blood spot (DBS) - based early infant diagnosis (EID), drug resistance (DR) genotyping, HIV-1 subtyping and incidence assays, have increased in recent years and their performance quality is closely monitored. Conclusion China has made significant progress in establishing a well-coordinated HIV laboratory network and QA systems. However, the coverage and intensity of HIV testing and quality assurance programmes need to be strengthened so as to ensure that more infected persons are diagnosed and that they receive timely prevention and treatment services. |
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