| Titre : | Height and Site-specific Cancer Risk : A Cohort Study of a Korean Adult Population. (2009) |
| Auteurs : | Joohon SUNG ; Shah EBRAHIM ; Debbie-A LAWLOR ; George-Davey Smith ; Yun-Mi SONG ; Medical Research Council Centre for Causal Analyses in Translational Epidemiology. University of Bristol. Bristol. GBR |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 170, n° 1, 2009) |
| Pagination : | 53-64 |
| Langues: | Anglais |
| Mots-clés : | Taille corporelle ; Facteur risque ; Cancer ; Risque ; Corée ; Adulte ; Population ; Epidémiologie ; Asie ; Homme |
| Résumé : | [BDSP. Notice produite par INIST-CNRS R0x88lkH. Diffusion soumise à autorisation]. To evaluate the association between height and risk of cancer in an East Asian, middle-income population, the authors followed up a cohort of 788,789 Koreans (449,214 men and 339,575 women) aged 40-64 years for cancer incidence between 1994 and 2003. Cox proportional hazards regression analysis was used to evaluate the association. Each 5-cm increment in height was associated with 5% and 7% higher risk of all-sites cancer in men and women, respectively, after adjustment for age, body mass index, and behavioral and socioeconomic factors. When the associations were evaluated for site-specific cancers, a positive association was observed for cancer of the colon and thyroid in both men and women. Among gender-specific cancers, prostate cancer was positively associated with height in men. In women, there was a positive association between height and cancers of the breast and ovary, which did not change even after additional adjustment for reproductive factors. Although more clarification is needed for some site-specific cancers, the same positive association of height with cancer in a middle-income Korean population as found in high-income Western populations supports the influence of early life environment on cancer development in adulthood. |
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