| Titre : | Is Complexity of Work Associated with Risk of Dementia ? The Canadian Study of Health and Aging. (2008) |
| Auteurs : | Edeltraut KROGER ; ANDEL (Ross) : USA. School of Aging Studies. University of South Florida. Tampa. FL. ; Zohra BENOUNISSA ; LAURIN (Danielle) : CAN. Faculty of Pharmacy. Laval University. Quebec City. PQ. ; LINDSAY (Joan) : CAN. Department of Epidemiology and Community Medicine. University of Ottawa. Ottawa. ON. ; René VERREAULT ; Faculty of Medicine. Laval University. Quebec City. PQ. CAN ; Laval University Geriatrics Research Unit. Centre de recherche du Cha. Quebec City. PQ. CAN |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 167, n° 7, 2008) |
| Pagination : | 820-830 |
| Langues: | Anglais |
| Mots-clés : | Travail ; Risque cumulé ; Facteur associé ; Association ; Facteur risque ; Risque ; Canada ; Personne âgée ; Vieillissement ; Activité ; Métier ; Statut social ; Amérique ; Homme ; Maladie dégénérative ; Amérique du Nord |
| Résumé : | [BDSP. Notice produite par INIST-CNRS R0xoGCEI. Diffusion soumise à autorisation]. The authors evaluated the association of complexity of work with data, people, and things with the incidence of dementia, Alzheimer's disease, and vascular dementia in the Canadian Study of Health and Aging, while adjusting for work-related physical activity. The Canadian Study of Health and Aging is a 10-year population study, from 1991 to 2001, of a representative sample of persons aged 65 years or older. Lifetime job history allowed application of complexity scores and classification of work-related physical activity. Analyses included 3,557 subjects, of whom 400 were incident dementia cases, including 299 with Alzheimer's disease and 93 with vascular dementia. In fully adjusted Cox regression models, high complexity of work with people or things reduced risk of dementia (hazard ratios were 0.66 (95% confidence interval : 0.44,0.98) and 0.72 (95% confidence interval : 0.52,0.99), respectively) but not Alzheimer's disease. For vascular dementia, hazard ratios were 0.36 (95% confidence interval : 0.15,0.90) for high complexity of work with people and 0.50 (95% confidence interval : 0.25,1.00) for high complexity of work with things. Subgroup analyses according to median duration (23 years) of principal occupation showed that associations with complexity varied according to duration of employment. High complexity of work appears to be associated with risk of dementia, but effects may vary according to subtype. |
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