| Titre : | Burden of HIV Infection Among Aboriginal Injection Drug Users in Vancouver, British Columbia. (2008) |
| Auteurs : | Evan WOOD ; BARNEY (Lucy) : CAN. British Columbia Centre for Disease Control. Vancouver. ; Thomas KERR ; Kathy LI ; Julio-Sg MONTANER ; STRATHDEE (Steffanie-A) : USA. Division of International Health and Cross Cultural Medicine. University of California. San Diego. ; Mark-W TYNDALL ; Ruth ZHANG ; British Columbia Centre for Excellence in Hiv Aids. St Paul's Hospital. Vancouver. CAN |
| Type de document : | Article |
| Dans : | American journal of public health (vol. 98, n° 3, 2008) |
| Pagination : | 515-519 |
| Langues: | Anglais |
| Mots-clés : | Toxicomanie ; Sida ; Voie intraveineuse ; Toxicomane ; Homme ; Virose ; Infection ; Canada ; Amérique ; Immunopathologie ; Amérique du Nord |
| Résumé : | [BDSP. Notice produite par INIST-CNRS kqGR0xEI. Diffusion soumise à autorisation]. Objectives. We sought to examine whether there were differential rates of HIV incidence among Aboriginal and non-Aboriginal injection drug users in a Canadian setting. Methods. Data were derived from 2 prospective cohort studies of injection drug users in Vancouver, British Columbia. Using the Kaplan-Meier method and Cox proportional hazards regression, we compared HIV incidence among Aboriginal and non-Aboriginal participants. Results. Overall, 2496 individuals were recruited between May 1996 and December 2005. Compared with that of non-Aboriginal persons, the baseline HIV prevalence was higher among Aboriginal persons (16.0% vs 25.1% ; P<. 001). Among participants who were HIV negative at baseline, the cumulative HIV incidence at 48 months was higher among Aboriginal persons (18.5% vs 9.5% ; P<. 001). In multivariate analyses, Aboriginal ethnicity was independently associated with elevated HIV incidence (relative hazard=1.59 ; 95% confidence interval=1.12,2.26 ; P=009). Conclusions. Aboriginal persons in Vancouver had a significantly elevated burden of HIV infection, which calls for a culturally sensitive and evidence-based response. Policymakers in other settings with at-risk Aboriginal populations should seek to avert similar public health emergencies by being proactive with evidence-based HIV-prevention programs. |
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