Titre :
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Intra-familial transmission of Helicobacter pylori infection in children of households with multiple generations in Vietnam. (2006)
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Auteurs :
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. VAN BANG NGUYEN ;
. DAC CAM PHUNG ;
Christophe DUPOND ;
. GIA KHANH NGUYEN ;
Nicolas KALACH ;
Odile Kremp ;
Karen OKRAINEC ;
Josette Raymond ;
Gwenaelle Vidal-Trecan ;
Hanoi Medical University. Hanoi. VNM
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Type de document :
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Article
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Dans :
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European journal of epidemiology (vol. 21, n° 6, 2006)
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Pagination :
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459-463
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Langues:
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Anglais
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Mots-clés :
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Bactériose
;
Infection
;
Famille
;
Helicobacter pylori
;
Bactérie
;
Enfant
;
Homme
;
Vietnam
;
Asie
;
Séropositivité
;
Relation intergénération
;
Cohabitation
;
Ménage
;
Epidémiologie
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Résumé :
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[BDSP. Notice produite par INIST-CNRS G4R0xcWq. Diffusion soumise à autorisation]. This community-based cross-sectional study in 533 participants from 135 households with multiple generations living in the same household aimed at investigating the relationship between Helicobacter pylori infection in children and the other household members. H. pylori infection in children was found significantly associated with the infection in mothers [OR (95% CI) : 2.50 (1.19-5.26) ], even after being adjusted for sex, age group and sibling number [adjusted OR (95% CI) : 2.47 (1.12-5.47) ]. It was also significantly associated with the infection in both parents [adjusted OR (95% CI) : 4.14 (1.29-13.23) ]. No significant association between H. pylori infection in the father, grandparent (s), uncle or aunt with that in their children was found. Results from the present study showed intra-familial transmission in a multi-generation population and supported the hypothesis of person-to-person transmission of H. pylori infection.
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