| Titre : | Postmenopausal Breast Cancer Risk and Dietary Patterns in the E3N-EPIC Prospective Cohort Study. (2009) |
| Auteurs : | Vanessa COTTET ; Marie-Christine BOUTRON-RUAULTT ; Francoise CLAVEL-CHAPELON ; Agnès Fournier ; Lionel Lafay ; Marina-S TOUILLAUD ; Mathilde Touvier ; Direction of Risk Assessment for Nutrition and Food Safety. (D.E.R.N.S.). Office of Scientific Support for Risk Assessment. (P.A.S.E.R.). French Food Safety Agency. (A.F.S.S.A.). Maisons Alfort. FRA ; Institut National de la Santé et de la Recherche Médicale. (I.N.S.E.R.M.). Equipe Région Inserm 20. Institut de Cancérologie Gustave Roussy. Villejuif. FRA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 170, n° 10, 2009) |
| Pagination : | 1257-1267 |
| Langues: | Anglais |
| Mots-clés : | Cancer ; Femme ; Sein ; Facteur risque ; Risque ; Régime alimentaire ; Etude prospective ; Statistique ; Epidémiologie ; Homme ; Alimentation |
| Résumé : | [BDSP. Notice produite par INIST-CNRS t9l9R0xH. Diffusion soumise à autorisation]. Since evidence relating diet to breast cancer risk is not sufficiently consistent to elaborate preventive proposals, the authors examined the association between dietary patterns and breast cancer risk in a large French cohort study. The analyses included 2,381 postmenopausal invasive breast cancer cases diagnosed during a median 9.7-year follow-up period (1993-2005) among 65,374 women from the E3N-EPIC cohort. Scores for dietary patterns were obtained by factor analysis, and breast cancer hazard ratios were estimated by Cox proportional hazards regression for the highest quartile of dietary pattern score versus the lowest. Two dietary patterns were identified : "alcohol/Western" (essentially meat products, French fries, appetizers, rice/pasta, potatoes, pulses, pizza/pies, canned fish, eggs, alcoholic beverages, cakes, mayonnaise, and butter/cream) and "healthy/Mediterranean" (essentially vegetables, fruits, seafood, olive oil, and sunflower oil). The first pattern was positively associated with breast cancer risk (hazard ratio=1.20,95% confidence interval (Cl) : 1.03,1.38 ; P=0.007 for linear trend), especially when tumors were estrogen receptor-positive/progesterone receptor-positive. The "healthy/Mediterranean" pattern was negatively associated with breast cancer risk (hazard ratio=0.85,95% Cl : 0.75,0.95 ; P=0.003 for linear trend), especially when tumors were estrogen receptor-positive/progesterone receptor-negative. Adherence to a diet comprising mostly fruits, vegetables, fish, and olive/sunflower oil, along with avoidance of Western-type foods, may contribute to a substantial reduction in postmenopausal breast cancer risk. |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact