Response to influenza vaccine in people with non-p... Catalogue en ligne

Titre :	Response to influenza vaccine in people with non-protective HI antibody titers. (2006)
Auteurs :	Vincenzo BALDO ; Tatjana BALDOVIN ; FLOREANI (Annarosa) : ITA. Department of Surgical and Gastroenterological Sciences. University of Padova. Padova. ; Michele MINUZZO ; Renzo TRIVELLO ; University of Padua. Institute of Hygiene. Department of Environmental Medicine and Public Health. Padova. ITA
Type de document :	Article
Dans :	European journal of epidemiology (vol. 21, n° 11, 2006)
Pagination :	843-845
Langues:	Anglais
Mots-clés :	Vaccin ; Grippe ; Virose ; Infection ; Homme ; Anticorps ; Prévention santé ; Epidémiologie
Résumé :	[BDSP. Notice produite par INIST-CNRS q9gR0x12. Diffusion soumise à autorisation]. The purpose of the study was to determine which factors correlate directly with response to vaccination in such a group of subjects with non-protective HI antibody titers before vaccination. Two vaccines were used, a subunit virus vaccine adjuvanted with MF59 and a split virus vaccine. The analysis indicated that immunization with vaccine adjuvanted with MF59 was an independent variable for immune response against A/H3N2 (OR : 3.51 ; 95% CI : 1.81-6.79) and B (OR : 2.31 ; 95% CI : 1.37-3.89). The results suggest that antibody response to vaccine is satisfactory in elderly people previously lacking a protective antibody titer, and that the adjuvanted vaccine reveals a better immunogenicity.

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