| Titre : | The first database comprised of flagellin gene (flaA) types of Campylobacter jejuni human clinical isolates from Greece. (2006) |
| Auteurs : | Anastassios IOANNIDIS ; Stylianos CHATZIPANAGIOTOU ; Vasiliki IOANNIDOU ; LEGAKIS (Nicholas-J) : GRC. Department of Microbiology. Athens Medical School. Athens. ; Chryssoula NICOLAOU ; Aeginition Hospital. Athens Medical School. Department of Clinical Microbiology. Athens. GRC |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 21, n° 11, 2006) |
| Pagination : | 823-829 |
| Langues: | Anglais |
| Mots-clés : | Gène ; Bactériose ; Infection ; Génétique ; Bactérie ; Homme ; Grèce ; Europe ; Sérotype ; Epidémiologie |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 5Mn26R0x. Diffusion soumise à autorisation]. Background : Flagellin subunit A gene (flaA) typing of Campylobacter has been recognized by several groups as a relatively simple and quick genotyping method. The present study aimed to create, for the first time in Greece, a database with flaA restriction patterns, which could be used for future epidemiological and clinical studies. A total of 207 C. jejuni clinical isolates of known serotype were collected from 5 general hospitals of the area of Attica, during the period 2000-2003. Results. The RFLP profiles of each strain were matched in 44 bins of 0 or 1. Thirty nine different flaA types, designated as flaA 1 GR to flaA 39 GR (GR : Greece) were found. There was no significant association of certain genotypes with certain serotypes. However flaA typing showed a remarkable discriminatory ability inside the non-typable (NT) group. Conclusions : Evaluating our results we observed (i) that there was no clonality of a certain flaA type among the strains and the serotypes examined and (ii) that the discriminatory ability of flaA typing was much better than that of serotyping. Giving a simple and detailed description of the data analysis, we are the first who publish the bin patterns for the flaA genotypes found. |
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