Titre : | Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection. (2007) |
Auteurs : | Paola PARRELLA ; Paola CORDIALI ; Aldo DI CARLO ; Vito-M FAZIO ; Antonietta-P GALLO ; Elvira GRANDONE ; Carolina GRAVINA ; Luciano MARIANI ; Maria-G MATERA ; Antonio PACHI ; Maria PRENCIPE ; Monica RINALDI ; Davide SERIPA ; Emanuela SIGNORI ; Patrizia STENTELLA ; Institute of Neurobiology and Molecular Medicine. Cnr-Artov. Rome. ITA ; Irccs "Casa Sollievo delta Sofferenza". Department of Research. Laboratory of Gerontology & Geriatrics. San Giovanni Rotondo. ITA ; Irccs "Casa Sollievo delta Sofferenza". Department of Research. Laboratory of Oncology. San Giovanni Rotondo. ITA ; University "La Sapienza". Clinic of Obstetrics and Gynecology. Rome. ITA ; University School of Medicine. Laboratory of Molecular Medicine and Biotechnology. Rome. ITA |
Type de document : | Article |
Dans : | European journal of epidemiology (vol. 22, n° 3, 2007) |
Pagination : | 159-162 |
Langues: | Anglais |
Mots-clés : | Infection ; Association ; Cancer ; Homme ; Génétique ; Virus ; Hôte ; Epidémiologie |
Résumé : | [BDSP. Notice produite par INIST-CNRS zEIUR0x5. Diffusion soumise à autorisation]. Genetic variants in the immunomodulatory gene mannose-binding lectin 2 (MBL2), were associated with risk, severity, and frequency of viral infections. In a case-control setting, we investigated the association of MBL2 functional polymorphisms with Human Papillomas Virus (HPV) infection. No differences between cases (HPV+) and controls (HPV-) were found in the distribution of each single genotypes or allele. Haplotype analysis did not show any difference between HPV+and HPV-groups. |