Titre : | Blood Pressure and Risk of Renal Cell Carcinoma in the European Prospective Investigation into Cancer and Nutrition. (2008) |
Auteurs : | Steffen WEIKERT ; Naomi ALLEN ; Aurelio BARRICARTE ; H. BAS BUENO-DE-MESQUITA ; Nikolaus BECKER ; Göran BERGLUND ; Sheila BINGHAM ; Heiner BOEING ; Miren DORRONSORO ; Pietro FERRARI ; Carlos-A GONZALEZ ; Goran HALLMANS ; Kay-Tee KHAW ; Jakob LINSEISEN ; Borje LJUNGBERG ; W.M. MONIQUE VERSCHUREN ; Theodore MOUNTOKALAKIS ; Teresa NORAT ; Anja OLSEN ; Kim OVERVAD ; Domenico PALLI ; Salvatore PANICO ; Petra-Hm PEETERS ; Tobias PISCHON ; Elio RIBOLI ; Sabina RINALDI ; Andrew RODDAM ; Sabina SIERI ; Anne TJONNELAND ; M.J. TORMO ; Dimitrios TRICHOPOULOS ; Antonia TRICHOPOULOU ; Paolo VINEIS ; Cornelia WEIKERT |
Type de document : | Article |
Dans : | American journal of epidemiology (vol. 167, n° 4, 2008) |
Pagination : | 438-446 |
Langues: | Anglais |
Mots-clés : | Pression artérielle ; Cancer ; Facteur risque ; Risque ; Europe ; Hypertension artérielle ; Homme ; Etude prospective ; Alimentation ; Nutrition ; Médicament antihypertenseur ; Rein ; Epidémiologie ; Appareil urinaire |
Résumé : | [BDSP. Notice produite par INIST-CNRS ePR0xqy7. Diffusion soumise à autorisation]. Elevated blood pressure has been implicated as a risk factor for renal cell carcinoma (RCC), but prospective studies were confined to men and did not consider the effect of antihypertensive medication. The authors examined the relation among blood pressure, antihypertensive medication, and RCC in the European Prospective Investigation into Cancer and Nutrition (EPIC). Blood pressure was measured in 296,638 women and men, recruited in eight European countries during 1992-1998,254,935 of whom provided information on antihypertensive medication. During a mean follow-up of 6.2 years, 250 cases of RCC were identified. Blood pressure was independently associated with risk of RCC. The relative risks for the highest versus the lowest category of systolic (>160 mmHg vs.=100 mmHg vs. |