Résumé :
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[BDSP. Notice produite par INIST-CNRS H8pR0xkp. Diffusion soumise à autorisation]. Long-chain oméga-3 polyunsaturated fatty acids (PUFAs) may have antineoplastic properties in the colon. The authors examined the association between intakes of different PUFAs and distal large bowel cancer in a population-based case-control study of 1,503 whites (716 cases ; 787 controls) and 369 African Americans (213 cases ; 156 controls) in North Carolina (2001-2006). Unconditional logistic regression was used to estimate odds ratios and 95% confidence intervals for distal large bowel cancer risk in relation to quartiles of PUFA intake. Increased consumption of long-chain oméga-3 PUFAs was associated with reduced risk of distal large bowel cancer in whites (multivariable odds ratios=0.88 (95% confidence interval (CI) : 0.63,1.22), 0.69 (95% CI : 0.49,0.98), and 0.49 (95% CI : 0.34,0.71) for second, third, and highest vs. lowest quartile) (Ptrend
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