Résumé :
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[BDSP. Notice produite par INIST-CNRS 89R0xCkE. Diffusion soumise à autorisation]. The authors examined the association between semen quality and caffeine intake among 2,554 young Danish men recruited when they were examined to determine their fitness for military service in 2001-2005. The men delivered a semen sample and answered a questionnaire including information about caffeine intake from various sources, from which total caffeine intake was calculated. Moderate caffeine and cola intakes (101-800 mg/day and<=14 0.5-L bottles of cola/week) compared with low intake (<100 mg/day, no cola intake) were not associated with semen quality. High cola (>14 0.5-L bottles/week) and/or caffeine (>800 mg/day) intake was associated with reduced sperm concentration and total sperm count, although only significant for cola. High-intake cola drinkers had an adjusted sperm concentration and total sperm count of 40 mill/mL (95% confidence interval (CI) : 32,51) and 121 mill (95% CI : 92,160), respectively, compared with 56 mill/mL (95% CI : 50,64) and 181 mill (95% CI : 156,210) in non-cola-drinkers, which could not be attributed to the caffeine they consumed because it was<140 mg/day. Therefore, the authors cannot exclude the possibility of a threshold above which cola, and possibly caffeine, negatively affects semen quality. Alternatively, the less healthy lifestyle of these men may explain these findings.
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