Titre :
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Chronic bronchitis and pesticide exposure : a case-control study in Lebanon. (2006)
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Auteurs :
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Pascale-R SALAMEH ;
Bernadette ABI SALEH ;
Isabelle BALDI ;
Patrick BROCHARD ;
WAKED (Mirna) : LBN. Faculty of Medicine. Balamand University. El Koura. ;
Lebanese University. Faculty of Public Health. Beirut. LBN ;
Victor Segalen Bordeaux 2 University. Isped. Faculty of Public Health. Bordeaux. FRA
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Type de document :
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Article
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Dans :
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European journal of epidemiology (vol. 21, n° 9, 2006)
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Pagination :
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681-688
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Langues:
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Anglais
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Mots-clés :
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Bronchite
;
Pesticide
;
Bronchopneumopathie obstructive
;
Exposition professionnelle
;
Enquête cas témoin
;
Epidémiologie
;
Liban
;
Asie
;
Appareil respiratoire
;
Symptôme
;
Homme
;
Santé environnementale
;
Symptôme respiratoire
;
Appareil respiratoire [pathologie]
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Résumé :
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[BDSP. Notice produite par INIST-CNRS 893R0xVc. Diffusion soumise à autorisation]. Objective : Pesticides are widely used toxics. The objective of the study is to evaluate the odds of exposure to pesticides in chronic bronchitis patients. Methods : Using the American Thoracic Society standardized questionnaire confirmed by medical diagnosis of chronic bronchitis, a case-control study was performed in Lebanon. Pesticide exposure was estimated and between groups comparison was made. Results : The study involved 262 controls and 110 chronic bronchitis outpatient subjects from 10 medical centers. Any exposure to pesticides was associated to chronic bronchitis (OR=2.46 [1.53-3.94] ; p<10-4). Occupational use presented the highest association (15.92 [3.50-72.41] ; p<10-4), followed by regional exposure (3.70 [2.05-6.70] ; p<10-4). Results were confirmed by multivariate and subgroup analysis. Conclusion : Pesticide exposure was associated with chronic bronchitis in Lebanese adults. Pesticides toxicological effects may explain chronic respiratory effects associations found with all exposure types.
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