Résumé :
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[BDSP. Notice produite par INIST-CNRS R0xJp64d. Diffusion soumise à autorisation]. BACKGROUND : Small body size at birth, as a marker of an adverse intrauterine environment, has recently emerged as an important risk factor for death from cardiovascular disease. Our aim was to study the relationship between small size at birth and all-cause and non-cardiovascular mortality, which has been poorly documented. METHODS : We studied 13 830 individuals born between 1924 and 1944 in Helsinki, Finland, at term as singletons. Dates and primary causes of death between 1971 and 1998 were obtained from the Finnish National Death Register. RESULTS : 1668 men and 671 women died during the follow-up at the mean age of 56.0 (range 26.7-74.9) years. Lower birthweight was associated with increased all-cause mortality in females (Odds ratio (OR) for 1 kg decrease in birthweight 1.25,95% CI 1.05-1.49 ; P=0.01) but not in males (OR 1.08 ; 0.96-1.19 ; P=0.2 ; P for sex-birthweight interaction=0.09). Similarly, short length at birth was a predictor of all-cause mortality in females (OR for 1 cm decrease 1.10 ; 1.05-1.15 ; P
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