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Titre :
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Body indices and basic vital signs in Helicobacter pylori positive and negative persons. (2007)
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Auteurs :
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Marcela KOPACOVA ;
Jan BURES ;
Tomas DOUDA ;
Jan HOLCIK ;
Ilona KOUPIL ;
Vladimir PALICKA ;
Oldrich POZLER ;
Stanislav REJCHRT ;
Bohumil SEIFERT ;
Viktor VORISEK ;
Pavel ZIVNY ;
Charles University in Praha. Institute of Clinical Biochemistry and Diagnostics. CZE ;
European Society for Primary Care Gastroenterology. INC ;
University Teaching Hospital. Faculty of Medicine. Hradec Kr lové. CZE
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Type de document :
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Article
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Dans :
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European journal of epidemiology (vol. 22, n° 1, Janvier 2007)
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Pagination :
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67-75
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Langues:
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Anglais
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Mots-clés :
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Urée
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Poids corporel
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Helicobacter pylori
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Bactérie
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Test respiratoire
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Taille corporelle
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Hypertension artérielle
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Homme
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Obésité
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Epidémiologie
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Anthropométrie
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Appareil circulatoire [pathologie]
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Maladie nutrition
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Résumé :
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[BDSP. Notice produite par INIST-CNRS R0xMLvey. Diffusion soumise à autorisation]. It has been hypothesized that Helicobacter pylori (Hp) infection may contribute to reduced stature, risk of hypertension or obesity. The aim was to evaluate body indices in Hp positive and negative persons. A total of 2436 subjects (4-100 years old) were tested for Hp status by 13C-urea breath test. Data on height and weight were collected for 84%, and blood pressure for 80% of the study subjects. The prevalence of Hp infection was 41.6%. The odds ratio for a 10-year increase in age was 1.21 (95% CI 1.17-1.25, p-value<0.001). Statistically significant negative association of Hp positivity with body height was most pronounced in the younger age groups, while a positive association of Hp positivity with body mass index was only seen in those aged 15+years. There was a negative effect of Hp positivity on systolic and diastolic blood pressure in subjects below 25 and a relatively strong positive effect on blood pressure in subjects over 65 years. Residual confounding by social characteristics as a possible explanation for the associations of Hp positivity with height and blood pressure cannot be excluded. Unmeasured factors related to social and family environment may cause the apparent association between Hp positivity and children's growth and blood pressure.
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