| Titre : | 25-Hydroxyvitamin D Status and Change in Physical Performance and Strength in Older Adults : The Health, Aging, and Body Composition Study. (2012) |
| Auteurs : | Denise-K HOUSTON ; Mary ANN JOHNSON ; Doug-C BAUER ; Jane-A CAULEY ; Peggy-M CAWTHON ; Tamara-B HARRIS ; Dorothy-B HAUSMAN ; Stephen-B KRITCHEVSKY ; M. KYLA SHEA ; Rebecca-H NEIBERG ; Gary-G SCHWARTZ ; Eleanor-M SIMONSICK ; Janet-A TOOZE ; Frances-A TYLAVSKY ; Marjolein VISSER ; Jeff-D WILLIAMSON ; Department of Biostatistical Sciences. Wake Forest School of Medicine. Winston Salem. NC. USA ; Department of Foods and Nutrition. College of Family and Consumer Sciences. University of Georgia. Athens. GEO ; Department of Internal Medicine. Wake Forest School of Medicine. Winston Salem. NC. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 176, n° 11, 2012) |
| Pagination : | 1025-1034 |
| Langues: | Anglais |
| Mots-clés : | Changement ; Personne âgée ; Vieillissement ; Muscle ; Epidémiologie ; Homme |
| Résumé : | [BDSP. Notice produite par INIST-CNRS kR0xHsI8. Diffusion soumise à autorisation]. Low 25-hydroxyvitamin D (25 (OH) D) concentrations are common among older adults and are associated with poorer physical performance and strength, but results from longitudinal studies have been inconsistent. The 25 (OH) D threshold for physical performance and strength was determined, and both cross-sectional and longitudinal associations between 25 (OH) D and physical performance and strength were examined, in men and women aged 71-80 years from the Health, Aging, and Body Composition Study (n=2,641). Baseline serum 25 (OH) D was measured in 1998-1999, and physical performance and strength were measured at baseline and at 2and 4-year follow-up. Piecewise regression models were used to determine 25 (OH) D thresholds. Linear regression and mixed models were used to examine cross-sectional and longitudinal associations. The 25 (OH) D thresholds were 70-80 nmol/L for physical performance and 55-70 nmol/L for strength. Participants with 25 (OH) D<50 nmol/L had poorer physical performance at baseline and at 2-and 4-year follow-up than participants with 25 (OH) D>75 nmol/L (P<0.01). Although physical performance and strength declined over 4 years of follow-up (P<0.0001), in general, the rate of decline was not associated with baseline 25 (OH) D. Older adults with low 25 (OH) D concentrations had poorer physical performance over 4 years of follow-up, but low 25 (OH) D concentrations were not associated with a faster rate of decline in physical performance or strength. |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact