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Patient preferences in randomised controlled trials : Conceptual framework and implications for research.

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Titre :	Patient preferences in randomised controlled trials : Conceptual framework and implications for research. (2005)
Auteurs :	BOWER (Peter) : GBR. Npcrdc. Manchester. ; KING (Michael) : GBR. Department of Mental Health Sciences. Royal Free and University College Medical School. ; Fiona LAMPE ; NAZARETH (Irwin) : GBR. Department of Primary Care and Population Sciences. Royal Free and University College Medical School. ; Bonnie SIBBALD ; University of Manchester. National Primary Care Research and Development Centre. Manchester. GBR
Type de document :	Article
Dans :	Social science and medicine (vol. 61, n° 3, 2005)
Pagination :	685-695
Langues:	Anglais
Mots-clés :	Homme ; Essai thérapeutique ; Méthodologie ; Consentement soins ; Ethique ; Recrutement
Résumé :	[BDSP. Notice produite par INIST-CNRS py0mtR0x. Diffusion soumise à autorisation]. Patient preferences have recently been highlighted as a potential threat to the validity of randomised controlled trials (RCTs). Although there have been significant methodological and statistical developments in relation to these issues, comparatively little attention has been paid to the development of a conceptual model concerning preferences and their effects on decision-making. This article describes the development of such a model, which was undertaken in parallel with a systematic review of the empirical data concerning preference effects. The model describes the concept of preference in terms of theoretical concepts from the psychological and economics literature, and describes a preliminary model of the development and operation of preferences in the context of RCTs. The paper then examines the implications of the model for informed consent and recruitment procedures. Key issues for future research are also outlined.