| Titre : | First general outbreak of Verocytotoxin-producing Escherichia coli O157 in Denmark. (2006) |
| Auteurs : | C. JENSEN ; S. ETHELBERG ; A. GERVELMEYER ; K. MOLBAK ; E.M. NIELSEN ; K.E. OLSEN |
| Type de document : | Article |
| Dans : | Eurosurveillance European communicable disease quarterly (vol. 11, n° 1-3, 2006/03) |
| Pagination : | 55-58 |
| Langues: | Anglais |
| Mots-clés : | Epidémie ; Danemark ; Lait ; Diarrhée ; Contamination aliment ; Pasteurisation ; Escherichia coli ; Enquête cas témoin |
| Résumé : | [BDSP. Notice produite par InVS h1R0xm1k. Diffusion soumise à autorisation]. This report describes the first general outbreak of verocytotoxin-producing Escherichia coli (VTEC) in Denmark. Twenty five patients, 18 children and seven adults, with culture-confirmed VTEC O157 : H-infection and indistinguishable pulsed-field gel electrophoresis DNA profiles, were identified during a six month period from September 2003 to March 2004. The outbreak strain possessed the virulence genes : eae, vtx1 and vtx2c. All patients but one presented with diarrhoea ; none developed haemolytic uraemic syndrome. The outbreak was restricted to Copenhagen and surrounding areas. A case-control study including 11 cases and 55 matched controls revealed an association between VTEC O157 : H-infection and shopping in a specific supermarket chain in Copenhagen and surrounding area, matched odds ratio (OR) : 8.7 (95% confidence interval (CI) : 1.1-71). After exclusion of three assumed secondary cases, only consumption of a particular kind of organic milk from a small dairy was associated with disease OR : 8.7 (95% CI 1.6-48). Environmental and microbiological investigations at the suspected dairy did not confirm the presence of the outbreak strain, but the outbreak stopped once the dairy was closed and thoroughly cleaned. |
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