Résumé :
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[BDSP. Notice produite par INIST-CNRS kR0x65Cy. Diffusion soumise à autorisation]. The authors sought to quantify the overall and race/ethnic-specific relations between prepregnancy body mass index and both preterm birth and vaginal inflammation. Data from a cohort of 11,392 women who enrolled in the multicenter Vaginal Infections and Prematurity Study (1984-1989) at 23-26 weeks'gestation were used. Compared with a prepregnancy body mass index of 22, a body mass index of 16 increased the risk of preterm birth by 90% (odds ratio=1.9,95% confidence interval (Cl) : 1.5,2.6), and a body mass index of 18 increased the risk by 40% (odds ratio=1.4,95% Cl : 1.2,1.7). Ethnicity substantially modified the magnitude of the body mass index effect and the shape of the preterm birth risk curve, with underweight having a greater impact on preterm birth among Blacks and Hispanics than among Whites. Low body mass index increased the risk of a high level of neutrophils (>5 per oil immersion field) and a high vaginal pH measurement (>5.0) among Black women ; for a body mass index of 16 versus 22, the odds ratio=1.7 (95% Cl : 1.1,2.6). Compared with Black women with a body mass index of 22, Blacks with a body mass index of 16 had a 1.7-fold increased risk for a high level of neutrophils and a high vaginal pH measurement, while those with a body mass index of 18 had a 1.3-fold increased risk.
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