| Titre : | Decrements in lung function related to arsenic in drinking water in West Bengal, India. (2005) |
| Auteurs : | Ondine-S VON EHRENSTEIN ; BALMES (John) : USA. Division of Occupational and Environmental Medicine. University of California. San Francisco. CA. ; Subhankar DAS ; Nilima GHOSH ; D.N. GUHA MAZUMDER ; HAQUE (Reina) : USA. Department of Research and Evaluation. Kaiser Permanente Southern California. Pasadena. CA. ; Meera HIRA-SMITH ; Sarbari LAHIRI ; Radhika PURUSHOTHAMAM ; Sambit SAMANTA ; Arabinda SIL ; Allan-H Smith ; . YAN YUAN ; Institute of Post Graduate Medical Education and Research. Kolkata. IND ; University of California. School of Public Health. Arsenic Health Effects Research Program. Berkeley. CA. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 162, n° 6, 2005) |
| Pagination : | 533-541 |
| Langues: | Anglais |
| Mots-clés : | Arsenic ; Eau consommation humaine ; Inde ; Asie ; Homme ; Symptôme ; Appareil respiratoire ; Respiration ; Polluant ; Santé environnementale ; Epidémiologie ; Pollution eau |
| Résumé : | [BDSP. Notice produite par INIST-CNRS OXPvHR0x. Diffusion soumise à autorisation]. During 1998-2000, the authors investigated relations between lung function, respiratory symptoms, and arsenic in drinking water among 287 study participants, including 132 with arsenic-caused skin lesions, in West Bengal, India. The source population involved 7,683 participants who had been surveyed for arsenic-related skin lesions in 1995-1996. Respiratory symptoms were increased among men with arsenic-caused skin lesions (versus those without lesions), particularly "shortness of breath at night" (odds ratio (OR)=2.8,95% confidence interval (Cl) : 1.1,7.6) and "morning cough" (OR=2.8,95% Cl : 1.2,6.6) in smokers and "shortness of breath ever" (OR=3.8,95% Cl : 0.7,20.6) in nonsmokers. Among men with skin lesions, the average adjusted forced expiratory volume in 1 second (FEV1) was reduced by 256.2 ml (95% Cl : 113.9,398.4 ; p<0.001) and the average adjusted forced vital capacity (FVC) was reduced by 287.8 ml (95% Cl : 134.9,440.8 ; p<0.001). In men, a 100-mug/liter increase in arsenic level was associated with a 45.0-ml decrease (95% Cl : 6.2,83.9) in FEV1 (p=0.02) and a 41.4-ml decrease (95% CI : - 0.7,83.5) in FVC (p=0.054). Women had lower risks than men of developing skin lesions and showed little evidence of respiratory effects. In this study, consumption of arsenic-contaminated water was associated with respiratory symptoms and reduced lung function in men, especially among those with arsenic-related skin lesions. |
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