Résumé :
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[BDSP. Notice produite par INIST-CNRS GpGoR0xl. Diffusion soumise à autorisation]. The authors examined the association between waist circumference and mortality among 154,776 men and 90,757 women aged 51-72 years at baseline (1996-1997) in the NIH-AARP Diet and Health Study. Additionally, the combined effects of waist circumference and body mass index (BMI ; weight (kg)/height (m) 2) were examined. All-cause mortality was assessed over 9 years of follow-up (1996-2005). After adjustment for BMI and other covariates, a large waist circumference (fifth quintile vs. second) was associated with an approximately 25% increased mortality risk (men : hazard ratio (HR)=1.22,95% confidence interval (Cl) : 1.15,1.29 ; women : HR=1.28,95% Cl : 1.16,1.41). The waist circumference-mortality association was found in persons with and without prevalent disease, in smokers and nonsmokers, and across different racial/ethnic groups (non-Hispanic Whites, non-Hispanic Blacks, Hispanics, and Asians). Compared with subjects with a combination of normal BMI (18.5-<25) and normal waist circumference, those in the normal-BMI group with a large waist circumference (men :>=102 cm ; women :>=88 cm) had an approximately 20% higher mortality risk (men : HR=1.23,95% Cl : 1.08,1.39 ; women : HR=1.22,95% Cl : 1.09,1.36). The finding that persons with a normal BMI but a large waist circumference had a higher mortality risk in this study suggests that increased waist circumference should be considered a risk factor for mortality, in addition to BMI.
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