| Titre : | Maternal and infant birth characteristics and hepatoblastoma. (2006) |
| Auteurs : | Colleen-C MCLAUGHLIN ; BAPTISTE (Mark-S) : USA. Division of Chronic Disease Prevention and Adult Health. New York State Department of Health. Albany. NY. ; NASCA (Philip-C) : USA. School of Public Health and Health Sciences. University of Massachusetts at Amherst. Amherst. MA. ; Maria-J SCHYMURA ; Michael-S ZDEB ; New York State Department of Health. New York State Cancer Registry. Albany. NY. USA ; State University of New York at Albany. School of Public Health. Albany. NY. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 163, n° 9, 2006) |
| Pagination : | 818-828 |
| Langues: | Anglais |
| Mots-clés : | Mère ; Nourrisson ; Homme ; Naissance ; Prématurité ; Age mère naissance ; Assurance maladie ; Procréation artificielle ; Epidémiologie ; Facteur risque ; Pauvreté ; Appareil digestif [pathologie] ; Foie [pathologie] ; Cancer ; Gestation [pathologie] ; Facteur socioéconomique |
| Résumé : | [BDSP. Notice produite par INIST-CNRS R0x8t1wh. Diffusion soumise à autorisation]. Hepatoblastoma is a rare embryonal tumor with unknown etiology. The authors conducted a case-cohort study using public health surveillance data sets to examine perinatal risk factors for hepatoblastoma. Hepatoblastoma cases (n=58) diagnosed between 1985 and 2001 were identified from the New York State Cancer Registry and were matched to electronic birth records for 1985-2001 from New York State, excluding New York City. Controls (n=6,056) were selected from the birth cohorts for the same years. Having a birth weight less than 1,000 g was associated with a strongly increased risk of hepatoblastoma (relative risk (RR)=56.9,95% confidence interval (Cl) : 24.0,130.7). After adjustment for birth weight, a moderately increased risk of hepatoblastoma was found for younger maternal age (<20 years vs. 20-29 years : RR=2.5,95% Cl : 1.0,5.5), presumptive use of infertility treatment (RR=9.2,95% Cl : 2.1,31.5), maternal smoking (RR=2.1,95% Cl : 1.0,4.2), and higher maternal prepregnancy body mass index (body mass index of 25-29 vs. 20-24 : RR=2.9,95% Cl : 1.2,7.6). |
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