Résumé :
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[BDSP. Notice produite par INIST-CNRS R0xDDCsG. Diffusion soumise à autorisation]. Prospective data on ethnic differences in hormone receptor-defined subtypes of breast cancer and their risk factor profiles are scarce. The authors examined the joint distributions of estrogen receptor (ER) and progesterone receptor (PR) status across 5 ethnic groups and the associations of established risk factors with ER/PR status in the Multiethnic Cohort Study (Hawaii and Los Angeles, California). During an average of 10.4 years of follow-up of 84,427 women between 1993-1996 and 2004/2005,2,543 breast cancer cases with data on ER/PR status were identified : 1,672 estrogen receptor-positive (ER+)/progesterone receptor-positive (PR+) ; 303 ER+/progesterone receptor-negative (PR-) ; 77 estrogen receptor-negative (ER-)/PR+and 491 ER-/PR-ER/PR status varied significantly across racial/ethnic groups even within the same tumor stage (for localized tumors, P
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