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Résumé :
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[BDSP. Notice produite par INIST-CNRS FoR0xnlG. Diffusion soumise à autorisation]. The authors report baseline findings and predictors of nevus count (log total nevi) at the completion of year 1 (2004) of the first known population-based, prospective study of nevi in a US cohort of children. Overall, 64% (n=443/691) of grade 5 students and their parents in Framingham, Massachusetts, completed surveys and underwent digital photography. Total nevus count was associated with skin and hair color and tendency to burn, as measured by a sun sensitivity index. In multivariate analyses, male gender (rate ratio (RR)=1.38,95% confidence interval (Cl) : 1.22,1.55 ; P<0.0001), spending 5-6 weekly hours outdoors between 10 AM and 4 PM (RR=1.13,95% Cl : 1.00,1.28 ; P=0.051), getting a painful sunburn once (RR=1.24,95% Cl : 0.98,1.57 ; P=0.073) and at least twice (RR=1.34,95% Cl : 0.99,1.82 ; P=0.061), and wearing a shirt at the beach or pool rarely (RR=1.29,95% Cl : 1.08,1.54 ; P=0.005), sometimes (RR=1.26,95% Cl : 1.01,1.57 ; P=0.041), and often and always (RR=1.32,95% Cl : 1.13,1.54 ; P=0.001) were associated with increased number of nevi. Identifying factors that predict the development of nevi will improve primary prevention efforts during early life.
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